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Brinp2 Gene Detail
Summary
  • Symbol
    Brinp2
  • Name
    bone morphogenic protein/retinoic acid inducible neural-specific 2
  • Synonyms
    6430517E21Rik, Fam5b, mKIAA1747
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443333
    NCBI Gene: 240843
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:158072839-158183896 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 68.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2711 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443333
 protein coding gene Chr1:158072835-158185096 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016634
 protein coding gene Chr1:163340260-163455957 (-)
A/J MGP_AJ_G0016615
 protein coding gene Chr1:156717269-156822607 (-)
AKR/J MGP_AKRJ_G0016581
 protein coding gene Chr1:161515491-161624658 (-)
BALB/cJ MGP_BALBcJ_G0016576
 protein coding gene Chr1:157247831-157351756 (-)
C3H/HeJ MGP_C3HHeJ_G0016400
 protein coding gene Chr1:161665574-161774876 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017037
 protein coding gene Chr1:168914559-169028393 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014746
 protein coding gene Chr1:148894834-148998240 (-)
CAST/EiJ MGP_CASTEiJ_G0015980
 protein coding gene Chr1:161194642-161334334 (-)
CBA/J MGP_CBAJ_G0016375
 protein coding gene Chr1:174904230-175019404 (-)
DBA/2J MGP_DBA2J_G0016481
 protein coding gene Chr1:155673074-155778397 (-)
FVB/NJ MGP_FVBNJ_G0016479
 protein coding gene Chr1:154115079-154226225 (-)
LP/J MGP_LPJ_G0016552
 protein coding gene Chr1:164431240-164545540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016504
 protein coding gene Chr1:182460738-182575147 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017073
 protein coding gene Chr1:161346695-161457779 (-)
PWK/PhJ MGP_PWKPhJ_G0015766
 protein coding gene Chr1:154764444-154893912 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015553
 protein coding gene Chr1:160121169-160244118 (-)
WSB/EiJ MGP_WSBEiJ_G0016042
 protein coding gene Chr1:161465788-161580456 (-)



Homology
more
  • Human Ortholog
    BRINP2, BMP/retinoic acid inducible neural specific 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BRINP2, BMP/retinoic acid inducible neural specific 2
  • Synonyms
    DBCCR1L2, FAM5B
  • Links
    NCBI Gene ID: 57795
    neXtProt AC: NX_Q9C0B6
    UniProt: Q9C0B6

  • Chr Location
    1q25.2; chr1:177170958-177282422 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human BRINP2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    7
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000004031 Ensembl Gene Model | MGI Sequence Detail 111058 C57BL/6J ±  kb
    transcript ENSMUST00000004133 Ensembl | MGI Sequence Detail 4167 Not Applicable  
    polypeptide ENSMUSP00000004133 Ensembl | MGI Sequence Detail 783 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000030437 BMP/retinoic acid-inducible neural-specific protein 2
      (term hierarchy)
    • InterPro Domains
      IPR033237 BMP/retinoic acid-inducible neural-specific protein
      IPR020864 Membrane attack complex component/perforin (MACPF) domain
    • GlyGen
      Q6DFY8 7 sites, 5 N-linked glycans (3 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3034853
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory