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Fbxl13 Gene Detail
Summary
  • Symbol
    Fbxl13
  • Name
    F-box and leucine-rich repeat protein 13
  • Synonyms
    4921539K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443416
    NCBI Gene: 320118
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:21688845-21850632 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 9.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5302 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443416
 protein coding gene Chr5:21688845-21850696 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029318
 protein coding gene Chr5:19035660-19213728 (-)
A/J MGP_AJ_G0029283
 protein coding gene Chr5:18420221-18584304 (-)
AKR/J MGP_AKRJ_G0029234
 protein coding gene Chr5:19121836-19289468 (-)
BALB/cJ MGP_BALBcJ_G0029295
 protein coding gene Chr5:18858029-19022377 (-)
C3H/HeJ MGP_C3HHeJ_G0029014
 protein coding gene Chr5:19192287-19361236 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029748
 protein coding gene Chr5:20442942-20617443 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026987
 protein coding gene Chr5:16479754-16639103 (-)
CAST/EiJ MGP_CASTEiJ_G0028426
 protein coding gene Chr5:18511566-18692281 (-)
CBA/J MGP_CBAJ_G0028981
 protein coding gene Chr5:20647408-20855844 (-)
DBA/2J MGP_DBA2J_G0029133
 protein coding gene Chr5:18704643-18868699 (-)
FVB/NJ MGP_FVBNJ_G0029091
 protein coding gene Chr5:18111853-18274962 (-)
LP/J MGP_LPJ_G0029217
 protein coding gene Chr5:19446961-19616330 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029119
 protein coding gene Chr5:21950686-22120078 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029781
 protein coding gene Chr5:18783254-18951908 (-)
PWK/PhJ MGP_PWKPhJ_G0028149
 protein coding gene Chr5:17749077-17921309 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027982
 protein coding gene Chr5:18137584-18313129 (-)
WSB/EiJ MGP_WSBEiJ_G0028506
 protein coding gene Chr5:18841127-19015137 (-)



Homology
more
  • Human Ortholog
    FBXL13, F-box and leucine rich repeat protein 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXL13, F-box and leucine rich repeat protein 13
  • Synonyms
    CFAP169, DRC6, Fbl13
  • Links
    NCBI Gene ID: 222235
    neXtProt AC: NX_Q8NEE6
    UniProt: Q8NEE6

  • Chr Location
    7q22.1; chr7:102811189-103074839 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Gene trapped
    1
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Fbxl13
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    46 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    8
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048520 Ensembl Gene Model | MGI Sequence Detail 161788 C57BL/6J ±  kb
transcript ENSMUST00000051358 Ensembl | MGI Sequence Detail 2531 Not Applicable  
polypeptide ENSMUSP00000052716 Ensembl | MGI Sequence Detail 790 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 18
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory