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Txnl4b Gene Detail
Summary
  • Symbol
    Txnl4b
  • Name
    thioredoxin-like 4B
  • Synonyms
    D530025J19Rik, Dim2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443724
    NCBI Gene: 234723
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:110292524-110300683 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 57.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    288 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443724
 protein coding gene Chr8:110292524-110300683 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034107
 protein coding gene Chr8:112166067-112174209 (+)
A/J MGP_AJ_G0034087
 protein coding gene Chr8:107606927-107616119 (+)
AKR/J MGP_AKRJ_G0034013
 protein coding gene Chr8:110775111-110783260 (+)
BALB/cJ MGP_BALBcJ_G0034080
 protein coding gene Chr8:107831203-107839361 (+)
C3H/HeJ MGP_C3HHeJ_G0033792
 protein coding gene Chr8:111485257-111493407 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034600
 protein coding gene Chr8:116131905-116140062 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031542
 protein coding gene Chr8:100658923-100667831 (+)
CAST/EiJ MGP_CASTEiJ_G0033119
 protein coding gene Chr8:111081977-111090148 (+)
CBA/J MGP_CBAJ_G0033765
 protein coding gene Chr8:120026876-120035028 (+)
DBA/2J MGP_DBA2J_G0033920
 protein coding gene Chr8:106948470-106956633 (+)
FVB/NJ MGP_FVBNJ_G0033865
 protein coding gene Chr8:105898074-105906226 (+)
LP/J MGP_LPJ_G0034011
 protein coding gene Chr8:112343087-112351234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033910
 protein coding gene Chr8:123047656-123055804 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034619
 protein coding gene Chr8:110737863-110746010 (+)
PWK/PhJ MGP_PWKPhJ_G0032821
 protein coding gene Chr8:106511671-106519953 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032660
 protein coding gene Chr8:109420805-109428782 (+)
WSB/EiJ MGP_WSBEiJ_G0033234
 protein coding gene Chr8:111421366-111429522 (+)



Homology
more
  • Human Ortholog
    TXNL4B, thioredoxin like 4B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TXNL4B, thioredoxin like 4B
  • Synonyms
    Dim2, DLP
  • Links
    NCBI Gene ID: 54957
    neXtProt AC: NX_Q9NX01
    UniProt: Q9NX01

  • Chr Location
    16q22.2; chr16:72084857-72094431 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    20
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234723 NCBI Gene Model | MGI Sequence Detail 8160 C57BL/6J ±  kb
transcript NM_175646 RefSeq | MGI Sequence Detail 1890 C57BL/6  
polypeptide Q8BUH1 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
Other
Accession IDs
less
MGI:2142590
References
more
  • Summaries
    All 31
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory