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Ssu2 Gene Detail
Summary
  • Symbol
    Ssu2
  • Name
    ssu-2 homolog
  • Synonyms
    D630042P16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443733
    NCBI Gene: 243612
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:112336285-112364984 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 52.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443733
 protein coding gene Chr6:112336283-112365160 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031106
 protein coding gene Chr6:114798995-114833078 (-)
A/J MGP_AJ_G0031075
 protein coding gene Chr6:110423883-110454695 (-)
AKR/J MGP_AKRJ_G0031006
 protein coding gene Chr6:113394542-113426752 (-)
BALB/cJ MGP_BALBcJ_G0031086
 protein coding gene Chr6:110379397-110407740 (-)
C3H/HeJ MGP_C3HHeJ_G0030622
 protein coding gene Chr6:70883985-70916720 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031545
 protein coding gene Chr6:117824101-117853137 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028709
 protein coding gene Chr6:107457218-107486696 (-)
CAST/EiJ MGP_CASTEiJ_G0030193
 protein coding gene Chr6:113828180-113858528 (-)
CBA/J MGP_CBAJ_G0030772
 protein coding gene Chr6:122431845-122476422 (-)
DBA/2J MGP_DBA2J_G0030925
 protein coding gene Chr6:109531778-109561580 (-)
FVB/NJ MGP_FVBNJ_G0030879
 protein coding gene Chr6:108511914-108545034 (-)
LP/J MGP_LPJ_G0031005
 protein coding gene Chr6:114858858-114893583 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030913
 protein coding gene Chr6:126761253-126791717 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031572
 protein coding gene Chr6:113414724-113445733 (-)
PWK/PhJ MGP_PWKPhJ_G0029909
 protein coding gene Chr6:108457538-108493029 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029737
 protein coding gene Chr6:112206963-112236334 (-)
WSB/EiJ MGP_WSBEiJ_G0030277
 protein coding gene Chr6:113777851-113811494 (-)



Homology
more
  • Human Ortholog
    SSUH2, ssu-2 homolog
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SSUH2, ssu-2 homolog
  • Synonyms
    C3orf32, fls485, SSU-2
  • Links
    NCBI Gene ID: 51066
    neXtProt AC: NX_Q9Y2M2
    UniProt: Q9Y2M2

  • Chr Location
    3p25.3; chr3:8619386-8745040 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Ssu2 mouse models

Human Disease Mouse Models
      
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous or homozygous for a knock-in allele exhibit abnormal tooth morphology, narrowed pulp cavity, increased dentin thickness, abnormal tooth attrition and collagenous attachment to the gum.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    745
  • Tissues
    13
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034387 Ensembl Gene Model | MGI Sequence Detail 28700 C57BL/6J ±  kb
    transcript ENSMUST00000238755 Ensembl | MGI Sequence Detail 1183 Not Applicable  
    polypeptide ENSMUSP00000158856 Ensembl | MGI Sequence Detail 375 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 6
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    12/10/2024
    MGI 6.24     		The Jackson Laboratory