About   Help   FAQ
Rnf152 Gene Detail
Summary
  • Symbol
    Rnf152
  • Name
    ring finger protein 152
  • Synonyms
    A930029B02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443787
    NCBI Gene: 320311
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:105204639-105284435 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 49.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2282 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443787
protein coding gene Chr1:105204639-105284665 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016365
protein coding gene Chr1:107367762-107457817 (-)
A/J MGP_AJ_G0016349
protein coding gene Chr1:103643717-103728082 (-)
AKR/J MGP_AKRJ_G0016309
protein coding gene Chr1:106470631-106558677 (-)
BALB/cJ MGP_BALBcJ_G0016305
protein coding gene Chr1:103737993-103818364 (-)
C3H/HeJ MGP_C3HHeJ_G0016132
protein coding gene Chr1:106891086-106980104 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016764
protein coding gene Chr1:111524636-111606792 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014482
protein coding gene Chr1:98013662-98089525 (-)
CAST/EiJ MGP_CASTEiJ_G0015714
protein coding gene Chr1:105825737-105904988 (-)
CBA/J MGP_CBAJ_G0016105
protein coding gene Chr1:115272369-115364901 (-)
DBA/2J MGP_DBA2J_G0016210
protein coding gene Chr1:102697341-102783946 (-)
FVB/NJ MGP_FVBNJ_G0016211
protein coding gene Chr1:101657086-101736739 (-)
LP/J MGP_LPJ_G0016284
protein coding gene Chr1:108635506-108723874 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016237
protein coding gene Chr1:119728262-119825211 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016803
protein coding gene Chr1:106551823-106636457 (-)
PWK/PhJ MGP_PWKPhJ_G0015501
protein coding gene Chr1:101757383-101840601 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015286
protein coding gene Chr1:105208600-105287386 (-)
WSB/EiJ MGP_WSBEiJ_G0015777
protein coding gene Chr1:106384026-106469134 (-)



Homology
more
  • Human Ortholog
    RNF152, ring finger protein 152
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF152, ring finger protein 152
  • Links
    NCBI Gene ID: 220441
    neXtProt AC: NX_Q8N8N0
    UniProt: Q8N8N0

  • Chr Location
    18q21.33; chr18:61808067-61894412 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Rnf152
  • Incidental Mutations
  • Find Mice (IMSR)
Mice homozygous for a null mutation display reduced starvation induced autophagy in MEFs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047496 Ensembl Gene Model | MGI Sequence Detail 79797 C57BL/6J ±  kb
transcript ENSMUST00000058688 Ensembl | MGI Sequence Detail 8492 Not Applicable  
polypeptide ENSMUSP00000050103 Ensembl | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 2
    cDNA 23

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:285783 Xiong MG, et al., RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization. EMBO Rep. 2020 Mar 4;21(3):e48860

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory