About   Help   FAQ
Phf21b Gene Detail
Summary
  • Symbol
    Phf21b
  • Name
    PHD finger protein 21B
  • Synonyms
    A730032D07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443812
    NCBI Gene: 271305
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:84669582-84740250 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 40.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2094 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443812
 protein coding gene Chr15:84669577-84740330 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022182
 protein coding gene Chr15:85592891-85665005 (-)
A/J MGP_AJ_G0022141
 protein coding gene Chr15:82428579-82499630 (-)
AKR/J MGP_AKRJ_G0022116
 protein coding gene Chr15:84843950-84920560 (-)
BALB/cJ MGP_BALBcJ_G0022147
 protein coding gene Chr15:82560080-82630381 (-)
C3H/HeJ MGP_C3HHeJ_G0021917
 protein coding gene Chr15:84802975-84875960 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022592
 protein coding gene Chr15:88850608-88925881 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020117
 protein coding gene Chr15:78783240-78855295 (-)
CAST/EiJ MGP_CASTEiJ_G0021439
 protein coding gene Chr15:85597268-85669334 (-)
CBA/J MGP_CBAJ_G0021884
 protein coding gene Chr15:91736704-91813108 (-)
DBA/2J MGP_DBA2J_G0022011
 protein coding gene Chr15:81901423-81972829 (-)
FVB/NJ MGP_FVBNJ_G0021990
 protein coding gene Chr15:80965321-81040769 (-)
LP/J MGP_LPJ_G0022082
 protein coding gene Chr15:85745490-85818068 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022010
 protein coding gene Chr15:96520173-96597646 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022607
 protein coding gene Chr15:84850683-84929334 (-)
PWK/PhJ MGP_PWKPhJ_G0021180
 protein coding gene Chr15:81911973-81983181 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021014
 protein coding gene Chr15:84563487-84642230 (-)
WSB/EiJ MGP_WSBEiJ_G0021488
 protein coding gene Chr15:85349627-85423117 (-)



Homology
more
  • Human Ortholog
    PHF21B, PHD finger protein 21B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF21B, PHD finger protein 21B
  • Synonyms
    BHC80L, PHF4
  • Links
    NCBI Gene ID: 112885
    neXtProt AC: NX_Q96EK2
    UniProt: Q96EK2

  • Chr Location
    22q13.31; chr22:44881162-45010005 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice exhibited impaired social memory and impaired long-term potentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    819
  • Tissues
    61
  • cDNA Data
    22
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000016624 Ensembl Gene Model | MGI Sequence Detail 70669 C57BL/6J ±  kb
    transcript ENSMUST00000159939 Ensembl | MGI Sequence Detail 3639 Not Applicable  
    polypeptide ENSMUSP00000125355 Ensembl | MGI Sequence Detail 487 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 22
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 1
      Phenotypes 27
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:328040 Chin EW, et al., The epigenetic reader PHF21B modulates murine social memory and synaptic plasticity-related genes. JCI Insight. 2022 Jul 22;7(14):e158081
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory