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Ric3 Gene Detail
Summary
  • Symbol
    Ric3
  • Name
    RIC3 acetylcholine receptor chaperone
  • Synonyms
    E130307J04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443887
    NCBI Gene: 320360
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:108633519-108682538 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 57.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1391 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443887
 protein coding gene Chr7:108633475-108682538 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032838
 protein coding gene Chr7:112437716-112487121 (-)
A/J MGP_AJ_G0032822
 protein coding gene Chr7:109673823-109723029 (-)
AKR/J MGP_AKRJ_G0032753
 protein coding gene Chr7:112406399-112454894 (-)
BALB/cJ MGP_BALBcJ_G0032826
 protein coding gene Chr7:109371467-109422259 (-)
C3H/HeJ MGP_C3HHeJ_G0032536
 protein coding gene Chr7:112445083-112498968 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033332
 protein coding gene Chr7:117136600-117187665 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030305
 protein coding gene Chr7:111262545-111308628 (-)
CAST/EiJ MGP_CASTEiJ_G0031864
 protein coding gene Chr7:103973233-104025180 (-)
CBA/J MGP_CBAJ_G0032509
 protein coding gene Chr7:120957849-121009367 (-)
DBA/2J MGP_DBA2J_G0032661
 protein coding gene Chr7:107782072-107831999 (-)
FVB/NJ MGP_FVBNJ_G0032614
 protein coding gene Chr7:107628197-107677621 (-)
LP/J MGP_LPJ_G0032755
 protein coding gene Chr7:113996368-114046713 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032646
 protein coding gene Chr7:122630428-122686907 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033353
 protein coding gene Chr7:111432540-111480457 (-)
PWK/PhJ MGP_PWKPhJ_G0031571
 protein coding gene Chr7:100585182-100634791 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031419
 protein coding gene Chr7:98114479-98166607 (-)
WSB/EiJ MGP_WSBEiJ_G0031977
 protein coding gene Chr7:112265874-112315072 (-)



Homology
more
  • Human Ortholog
    RIC3, RIC3 acetylcholine receptor chaperone
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIC3, RIC3 acetylcholine receptor chaperone
  • Synonyms
    AYST720, PRO1385, RIC-3
  • Links
    NCBI Gene ID: 79608
    neXtProt AC: NX_Q7Z5B4
    UniProt: Q7Z5B4

  • Chr Location
    11p15.4; chr11:8092965-8169055 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048330 Ensembl Gene Model | MGI Sequence Detail 49020 C57BL/6J ±  kb
transcript ENSMUST00000055993 Ensembl | MGI Sequence Detail 5281 Not Applicable  
polypeptide ENSMUSP00000056990 Ensembl | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013994 protein RIC-3
    (term hierarchy)
  • InterPro Domains
    IPR026160 Resistance to inhibitors of cholinesterase protein 3
    IPR032763 Resistance to inhibitors of cholinesterase protein 3, N-terminal
  • GlyGen
    Q8BPM6 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:304046 Deshpande A, et al., Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of alpha7 Nicotinic Receptors in Mouse Brain?. Biomolecules. 2020 Mar 19;10(3):470
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory