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Tmem215 Gene Detail
Summary
  • Symbol
    Tmem215
  • Name
    transmembrane protein 215
  • Synonyms
    A930001M12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444167
    NCBI Gene: 320500
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:40472180-40475653 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 20.28 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444167
 protein coding gene Chr4:40472180-40477168 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028144
 protein coding gene Chr4:38338086-38343029 (+)
A/J MGP_AJ_G0028102
 protein coding gene Chr4:36917741-36922674 (+)
AKR/J MGP_AKRJ_G0028065
 protein coding gene Chr4:37828930-37833881 (+)
BALB/cJ MGP_BALBcJ_G0028114
 protein coding gene Chr4:37221227-37226180 (+)
C3H/HeJ MGP_C3HHeJ_G0027842
 protein coding gene Chr4:38380428-38385351 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028555
 protein coding gene Chr4:39796323-39802868 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025896
 protein coding gene Chr4:34591608-34596462 (+)
CAST/EiJ MGP_CASTEiJ_G0027298
 protein coding gene Chr4:38064940-38071263 (+)
CBA/J MGP_CBAJ_G0027814
 protein coding gene Chr4:41118108-41123111 (+)
DBA/2J MGP_DBA2J_G0027958
 protein coding gene Chr4:36840609-36845632 (+)
FVB/NJ MGP_FVBNJ_G0027925
 protein coding gene Chr4:36166533-36171550 (+)
LP/J MGP_LPJ_G0028066
 protein coding gene Chr4:38408639-38413354 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027958
 protein coding gene Chr4:44477210-44482184 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028614
 protein coding gene Chr4:37944336-37949279 (+)
PWK/PhJ MGP_PWKPhJ_G0027016
 protein coding gene Chr4:36824889-36829966 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026844
 protein coding gene Chr4:37667125-37673823 (+)
WSB/EiJ MGP_WSBEiJ_G0027374
 protein coding gene Chr4:37913036-37922224 (+)



Homology
more
  • Human Ortholog
    TMEM215, transmembrane protein 215
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM215, transmembrane protein 215
  • Links
    NCBI Gene ID: 401498
    neXtProt AC: NX_Q68D42
    UniProt: Q68D42

  • Chr Location
    9p21.1; chr9:32783540-32789201 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Tmem215
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320500 NCBI Gene Model | MGI Sequence Detail 3474 C57BL/6J ±  kb
transcript NM_177175 RefSeq | MGI Sequence Detail 3218 C57BL/6  
polypeptide A7E1Z1 UniProt | EBI | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:302188 Liu Y, et al., Transmembrane protein 215 promotes angiogenesis by maintaining endothelial cell survival. J Cell Physiol. 2019 Jun;234(6):9525-9534
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory