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Col6a6 Gene Detail
Summary
  • Symbol
    Col6a6
  • Name
    collagen, type VI, alpha 6
  • Synonyms
    E330026B02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444259
    NCBI Gene: 245026
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:105566616-105705413 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 56.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4791 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444259
 protein coding gene Chr9:105565008-105705413 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035217
 protein coding gene Chr9:107424891-107577598 (-)
A/J MGP_AJ_G0035197
 protein coding gene Chr9:103560718-103703478 (-)
AKR/J MGP_AKRJ_G0035129
 protein coding gene Chr9:106138307-106286198 (-)
BALB/cJ MGP_BALBcJ_G0035190
 protein coding gene Chr9:103249566-103393948 (-)
C3H/HeJ MGP_C3HHeJ_G0034900
 protein coding gene Chr9:106539035-106691014 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035710
 protein coding gene Chr9:110396896-110548057 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032608
 protein coding gene Chr9:101074595-101215865 (-)
CAST/EiJ MGP_CASTEiJ_G0034212
 protein coding gene Chr9:106438453-106584956 (-)
CBA/J MGP_CBAJ_G0034869
 protein coding gene Chr9:114247307-114409954 (-)
DBA/2J MGP_DBA2J_G0035030
 protein coding gene Chr9:103030718-103173798 (-)
FVB/NJ MGP_FVBNJ_G0034978
 protein coding gene Chr9:101801440-101944991 (-)
LP/J MGP_LPJ_G0035106
 protein coding gene Chr9:107645673-107798669 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035017
 protein coding gene Chr9:115943809-116092697 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035732
 protein coding gene Chr9:106389940-106538853 (-)
PWK/PhJ MGP_PWKPhJ_G0033919
 protein coding gene Chr9:103323621-103470015 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033754
 protein coding gene Chr9:106439547-106585597 (-)
WSB/EiJ MGP_WSBEiJ_G0034332
 protein coding gene Chr9:106276297-106425185 (-)



Homology
more
  • Human Ortholog
    COL6A6, collagen type VI alpha 6 chain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COL6A6, collagen type VI alpha 6 chain
  • Links
    NCBI Gene ID: 131873
    neXtProt AC: NX_A6NMZ7
    UniProt: A6NMZ7

  • Chr Location
    3q22.1; chr3:130516720-130677044 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    32
  • cDNA Data
    4
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 245026 NCBI Gene Model | MGI Sequence Detail 138798 C57BL/6J ±  kb
transcript NM_001102607 RefSeq | MGI Sequence Detail 7098 C57BL/6  
polypeptide Q8C6K9 UniProt | EBI | MGI Sequence Detail 2265 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000005719 collagen alpha-6(VI) chain
    (term hierarchy)
  • InterPro Domains
    IPR008160 Collagen triple helix repeat
    IPR052229 Collagen VI and Biomineralization Protein PIF
    IPR036465 von Willebrand factor A-like domain superfamily
    IPR002035 von Willebrand factor, type A
  • GlyGen
    Q8C6K9 6 sites, 3 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 7
    cDNA 4
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:343800 Souali-Crespo S, et al., Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis. Development. 2023 Dec 15;150(24)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory