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Rnf214 Gene Detail
Summary
  • Symbol
    Rnf214
  • Name
    ring finger protein 214
  • Synonyms
    D130054N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444451
    NCBI Gene: 235315
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:45774723-45818209 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 25.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    891 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444451
 protein coding gene Chr9:45768067-45818209 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034742
 protein coding gene Chr9:44455963-44503408 (-)
A/J MGP_AJ_G0034723
 protein coding gene Chr9:43207972-43251943 (-)
AKR/J MGP_AKRJ_G0034650
 protein coding gene Chr9:44091615-44135174 (-)
BALB/cJ MGP_BALBcJ_G0034714
 protein coding gene Chr9:42931237-42975553 (-)
C3H/HeJ MGP_C3HHeJ_G0034425
 protein coding gene Chr9:44548769-44610788 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035235
 protein coding gene Chr9:45740939-45788633 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032149
 protein coding gene Chr9:42749235-42790188 (-)
CAST/EiJ MGP_CASTEiJ_G0033747
 protein coding gene Chr9:44410644-44461247 (-)
CBA/J MGP_CBAJ_G0034397
 protein coding gene Chr9:47414335-47467930 (-)
DBA/2J MGP_DBA2J_G0034556
 protein coding gene Chr9:43081962-43125440 (-)
FVB/NJ MGP_FVBNJ_G0034497
 protein coding gene Chr9:42349936-42393256 (-)
LP/J MGP_LPJ_G0034637
 protein coding gene Chr9:44783163-44826921 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034541
 protein coding gene Chr9:49189831-49243169 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035256
 protein coding gene Chr9:44000793-44048768 (-)
PWK/PhJ MGP_PWKPhJ_G0033452
 protein coding gene Chr9:42987219-43032225 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033288
 protein coding gene Chr9:44325476-44373534 (-)
WSB/EiJ MGP_WSBEiJ_G0033860
 protein coding gene Chr9:44052428-44097072 (-)



Homology
more
  • Human Ortholog
    RNF214, ring finger protein 214
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF214, ring finger protein 214
  • Links
    NCBI Gene ID: 257160
    neXtProt AC: NX_Q8ND24
    UniProt: Q8ND24

  • Chr Location
    11q23.3; chr11:117232625-117286454 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042790 Ensembl Gene Model | MGI Sequence Detail 43487 C57BL/6J ±  kb
    transcript ENSMUST00000162369 Ensembl | MGI Sequence Detail 3517 Not Applicable  
    polypeptide ENSMUSP00000149889 Ensembl | MGI Sequence Detail 714 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 6
    References
    more
    • Summaries
      All 27
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory