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Cilp Gene Detail
Summary
  • Symbol
    Cilp
  • Name
    cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Synonyms
    C130036G17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444507
    NCBI Gene: 214425
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65172462-65187887 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    509 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444507
 protein coding gene Chr9:65172462-65187896 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034952
 protein coding gene Chr9:64984718-65000142 (+)
A/J MGP_AJ_G0034932
 protein coding gene Chr9:62800658-62816079 (+)
AKR/J MGP_AKRJ_G0034862
 protein coding gene Chr9:64273250-64291104 (+)
BALB/cJ MGP_BALBcJ_G0034925
 protein coding gene Chr9:62522702-62538681 (+)
C3H/HeJ MGP_C3HHeJ_G0034635
 protein coding gene Chr9:64807594-64823011 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035444
 protein coding gene Chr9:66759204-66774670 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032355
 protein coding gene Chr9:62446896-62463032 (+)
CAST/EiJ MGP_CASTEiJ_G0033956
 protein coding gene Chr9:64999114-65016005 (+)
CBA/J MGP_CBAJ_G0034606
 protein coding gene Chr9:69082700-69098118 (+)
DBA/2J MGP_DBA2J_G0034765
 protein coding gene Chr9:62573109-62588523 (+)
FVB/NJ MGP_FVBNJ_G0034707
 protein coding gene Chr9:61893064-61908693 (+)
LP/J MGP_LPJ_G0034848
 protein coding gene Chr9:65266365-65281782 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034749
 protein coding gene Chr9:70326471-70341896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035466
 protein coding gene Chr9:64382935-64398352 (+)
PWK/PhJ MGP_PWKPhJ_G0033660
 protein coding gene Chr9:62769400-62786058 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033494
 protein coding gene Chr9:64665397-64680729 (+)
WSB/EiJ MGP_WSBEiJ_G0034069
 protein coding gene Chr9:64282579-64297997 (+)



Homology
more
  • Human Ortholog
    CILP, cartilage intermediate layer protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CILP, cartilage intermediate layer protein
  • Synonyms
    CILP-1, CILP1, HsT18872
  • Links
    NCBI Gene ID: 8483
    neXtProt AC: NX_O75339
    UniProt: O75339

  • Chr Location
    15q22.31; chr15:65194760-65211473 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CILP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    25
  • cDNA Data
    21
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042254 Ensembl Gene Model | MGI Sequence Detail 15426 C57BL/6J ±  kb
transcript ENSMUST00000048762 Ensembl | MGI Sequence Detail 4153 Not Applicable  
polypeptide ENSMUSP00000036631 Ensembl | MGI Sequence Detail 1250 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 21
    Primer pair 4
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory