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Slc9a7 Gene Detail
Summary
  • Symbol
    Slc9a7
  • Name
    solute carrier family 9 (sodium/hydrogen exchanger), member 7
  • Synonyms
    A530087D17Rik, NHE7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444530
    NCBI Gene: 236727
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:19971993-20158046 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 15.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4310 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444530
 protein coding gene ChrX:19965090-20158274 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035588
 protein coding gene ChrX:14974679-15161589 (-)
A/J MGP_AJ_G0035565
 protein coding gene ChrX:15089325-15268741 (-)
AKR/J MGP_AKRJ_G0035498
 protein coding gene ChrX:15559584-15770150 (-)
BALB/cJ MGP_BALBcJ_G0035558
 protein coding gene ChrX:14815496-15019240 (-)
C3H/HeJ MGP_C3HHeJ_G0035276
 protein coding gene ChrX:15179904-15369207 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036094
 protein coding gene ChrX:15380509-15564943 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032958
 protein coding gene ChrX:13336004-13521836 (-)
CAST/EiJ MGP_CASTEiJ_G0034567
 protein coding gene ChrX:14509075-14699742 (-)
CBA/J MGP_CBAJ_G0035245
 protein coding gene ChrX:16072294-16281591 (-)
DBA/2J MGP_DBA2J_G0035397
 protein coding gene ChrX:14882272-15070784 (-)
FVB/NJ MGP_FVBNJ_G0035343
 protein coding gene ChrX:14787886-14975888 (-)
LP/J MGP_LPJ_G0035479
 protein coding gene ChrX:15202457-15398365 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035387
 protein coding gene ChrX:16284410-16513195 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036101
 protein coding gene ChrX:14891614-15077458 (-)
PWK/PhJ MGP_PWKPhJ_G0034268
 protein coding gene ChrX:14079003-14267243 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034108
 protein coding gene ChrX:14872087-15057042 (-)
WSB/EiJ MGP_WSBEiJ_G0034702
 protein coding gene ChrX:14778323-14964434 (-)



Homology
more
  • Human Ortholog
    SLC9A7, solute carrier family 9 member A7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC9A7, solute carrier family 9 member A7
  • Synonyms
    MRX108, NHE-7, NHE7, SLC9A6
  • Links
    NCBI Gene ID: 84679
    neXtProt AC: NX_Q96T83
    UniProt: Q96T83

  • Chr Location
    Xp11.3-p11.23; chrX:46599251-46759118 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC9A7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    23
  • cDNA Data
    14
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037341 Ensembl Gene Model | MGI Sequence Detail 186054 C57BL/6J ±  kb
transcript ENSMUST00000072451 Ensembl | MGI Sequence Detail 2512 Not Applicable  
polypeptide ENSMUSP00000072274 Ensembl | MGI Sequence Detail 726 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory