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Gprin2 Gene Detail
Summary
  • Symbol
    Gprin2
  • Name
    G protein regulated inducer of neurite outgrowth 2
  • Synonyms
    C130040D06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444560
    NCBI Gene: 432839
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:33907645-33923610 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 20.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    572 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444560
 protein coding gene Chr14:33907645-33923649 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021168
 protein coding gene Chr14:27536921-27544082 (-)
A/J MGP_AJ_G0021116
 protein coding gene Chr14:26471477-26478669 (-)
AKR/J MGP_AKRJ_G0021093
 protein coding gene Chr14:27647783-27654975 (-)
BALB/cJ MGP_BALBcJ_G0021120
 protein coding gene Chr14:26654135-26661327 (-)
C3H/HeJ MGP_C3HHeJ_G0020903
 protein coding gene Chr14:27563853-27571045 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021552
 protein coding gene Chr14:28592783-28599975 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019114
 protein coding gene Chr14:26505013-26512140 (-)
CAST/EiJ MGP_CASTEiJ_G0020428
 protein coding gene Chr14:27382078-27389241 (-)
CBA/J MGP_CBAJ_G0020870
 protein coding gene Chr14:29621626-29628818 (-)
DBA/2J MGP_DBA2J_G0020992
 protein coding gene Chr14:26508168-26515360 (-)
FVB/NJ MGP_FVBNJ_G0020976
 protein coding gene Chr14:26468790-26475982 (-)
LP/J MGP_LPJ_G0021061
 protein coding gene Chr14:27869448-27876613 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021002
 protein coding gene Chr14:28775711-28782903 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021585
 protein coding gene Chr14:27481933-27489125 (-)
PWK/PhJ MGP_PWKPhJ_G0020176
 protein coding gene Chr14:25999702-26006949 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020000
 protein coding gene Chr14:27082360-27091993 (-)
WSB/EiJ MGP_WSBEiJ_G0020483
 protein coding gene Chr14:27537195-27544387 (-)



Homology
more
  • Human Ortholog
    GPRIN2, G protein regulated inducer of neurite outgrowth 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPRIN2, G protein regulated inducer of neurite outgrowth 2
  • Synonyms
    GRIN2, KIAA0514
  • Links
    NCBI Gene ID: 9721
    neXtProt AC: NX_O60269
    UniProt: O60269

  • Chr Location
    10q11.22; chr10:46541736-46557596 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071531 Ensembl Gene Model | MGI Sequence Detail 15966 C57BL/6J ±  kb
transcript ENSMUST00000226613 Ensembl | MGI Sequence Detail 10354 Not Applicable  
polypeptide ENSMUSP00000154640 Ensembl | MGI Sequence Detail 455 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR026646 G protein-regulated inducer of neurite outgrowth
    IPR032745 G protein-regulated inducer of neurite outgrowth, C-terminal
  • GlyGen
    A0A2I3BRN2 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685132
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:353307 Ratsika A, et al., Maternal high-fat diet-induced microbiota changes are associated with alterations in embryonic brain metabolites and adolescent behaviour. Brain Behav Immun. 2024 Jul 18;121:317-330
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory