About   Help   FAQ
Ccdc174 Gene Detail
Summary
  • Symbol
    Ccdc174
  • Name
    coiled-coil domain containing 174
  • Synonyms
    C130022K22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444652
    NCBI Gene: 232236
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:91855034-91876824 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 40.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    698 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444652
 protein coding gene Chr6:91819983-91876830 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031052
 protein coding gene Chr6:93503103-93524911 (+)
A/J MGP_AJ_G0031021
 protein coding gene Chr6:89936299-89959275 (+)
AKR/J MGP_AKRJ_G0030952
 protein coding gene Chr6:92423960-92447216 (+)
BALB/cJ MGP_BALBcJ_G0031032
 protein coding gene Chr6:89901600-89923750 (+)
C3H/HeJ MGP_C3HHeJ_G0030676
 protein coding gene Chr6:91977800-92000273 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031491
 protein coding gene Chr6:95919265-95941550 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028658
 protein coding gene Chr6:87921481-87942515 (+)
CAST/EiJ MGP_CASTEiJ_G0030139
 protein coding gene Chr6:92555275-92577799 (+)
CBA/J MGP_CBAJ_G0030718
 protein coding gene Chr6:99493191-99516350 (+)
DBA/2J MGP_DBA2J_G0030871
 protein coding gene Chr6:89115820-89137505 (+)
FVB/NJ MGP_FVBNJ_G0030825
 protein coding gene Chr6:88331614-88353370 (+)
LP/J MGP_LPJ_G0030951
 protein coding gene Chr6:93456975-93480641 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030859
 protein coding gene Chr6:103535928-103559417 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031518
 protein coding gene Chr6:92275220-92297675 (+)
PWK/PhJ MGP_PWKPhJ_G0029855
 protein coding gene Chr6:88074664-88096149 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029684
 protein coding gene Chr6:91185941-91206615 (+)
WSB/EiJ MGP_WSBEiJ_G0030223
 protein coding gene Chr6:92751375-92773593 (+)



Homology
more
  • Human Ortholog
    CCDC174, coiled-coil domain containing 174
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC174, coiled-coil domain containing 174
  • Synonyms
    C3orf19, ctr1, HSPC212, IHPM, IHPMR
  • Links
    NCBI Gene ID: 51244
    neXtProt AC: NX_Q6PII3
    UniProt: Q6PII3

  • Chr Location
    3p25.1; chr3:14651762-14672659 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Spontaneous
    1
  • Transgenic
    1
  • Genomic Mutations
    1 involving Ccdc174
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    20 strains or lines available
Mice homozygous for a transgenic gene disruption may exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    33
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034083 Ensembl Gene Model | MGI Sequence Detail 21791 C57BL/6J ±  kb
transcript ENSMUST00000037783 Ensembl | MGI Sequence Detail 1752 Not Applicable  
polypeptide ENSMUSP00000049280 Ensembl | MGI Sequence Detail 467 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory