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Tmem154 Gene Detail
Summary
  • Symbol
    Tmem154
  • Name
    transmembrane protein 154
  • Synonyms
    9930117H01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444725
    NCBI Gene: 320782
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:84573499-84611882 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 37.70 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1271 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444725
protein coding gene Chr3:84573499-84611882 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027346
protein coding gene Chr3:84617876-84662617 (+)
A/J MGP_AJ_G0027310
protein coding gene Chr3:81777032-81818266 (+)
AKR/J MGP_AKRJ_G0027276
protein coding gene Chr3:83711583-83751604 (+)
BALB/cJ MGP_BALBcJ_G0027319
protein coding gene Chr3:81857260-81897054 (+)
C3H/HeJ MGP_C3HHeJ_G0027063
protein coding gene Chr3:84024083-84064844 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027765
protein coding gene Chr3:87756905-87804391 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025118
protein coding gene Chr3:77453446-77492192 (+)
CAST/EiJ MGP_CASTEiJ_G0026510
protein coding gene Chr3:84213905-84260027 (+)
CBA/J MGP_CBAJ_G0027038
protein coding gene Chr3:90708975-90754940 (+)
DBA/2J MGP_DBA2J_G0027174
protein coding gene Chr3:81290966-81330523 (+)
FVB/NJ MGP_FVBNJ_G0027142
protein coding gene Chr3:79573294-79612325 (+)
LP/J MGP_LPJ_G0027282
protein coding gene Chr3:85573026-85618539 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027161
protein coding gene Chr3:97025380-97069674 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027823
protein coding gene Chr3:83517682-83558790 (+)
PWK/PhJ MGP_PWKPhJ_G0026244
protein coding gene Chr3:81077003-81117090 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026060
protein coding gene Chr3:82695189-82738748 (+)
WSB/EiJ MGP_WSBEiJ_G0026588
protein coding gene Chr3:83878729-83924879 (+)



Homology
more
  • Human Ortholog
    TMEM154, transmembrane protein 154
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM154, transmembrane protein 154
  • Links
    NCBI Gene ID: 201799
    neXtProt AC: NX_Q6P9G4
    UniProt: Q6P9G4

  • Chr Location
    4q31.3; chr4:152618628-152680012 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmem154
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 320782 NCBI Gene Model | MGI Sequence Detail 38384 C57BL/6J ±  kb
transcript NM_177260 RefSeq | MGI Sequence Detail 3342 C57BL/6  
polypeptide Q8C4Q9 UniProt | EBI | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Diseases 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory