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Fkbp15 Gene Detail
Summary
  • Symbol
    Fkbp15
  • Name
    FK506 binding protein 15
  • Synonyms
    C430014M02Rik, FKBP133, mKIAA0674
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444782
    NCBI Gene: 338355
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62218579-62278785 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 33.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1419 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444782
 protein coding gene Chr4:62218579-62278828 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028348
 protein coding gene Chr4:61277875-61340494 (-)
A/J MGP_AJ_G0028309
 protein coding gene Chr4:59059033-59118790 (-)
AKR/J MGP_AKRJ_G0028258
 protein coding gene Chr4:60695804-60758755 (-)
BALB/cJ MGP_BALBcJ_G0028329
 protein coding gene Chr4:59234483-59295410 (-)
C3H/HeJ MGP_C3HHeJ_G0028047
 protein coding gene Chr4:61201390-61265399 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028769
 protein coding gene Chr4:63384854-63444696 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026075
 protein coding gene Chr4:56351676-56410152 (-)
CAST/EiJ MGP_CASTEiJ_G0027483
 protein coding gene Chr4:59136191-59198563 (-)
CBA/J MGP_CBAJ_G0028014
 protein coding gene Chr4:65572259-65641730 (-)
DBA/2J MGP_DBA2J_G0028164
 protein coding gene Chr4:58917425-58976978 (-)
FVB/NJ MGP_FVBNJ_G0028129
 protein coding gene Chr4:58164203-58223664 (-)
LP/J MGP_LPJ_G0028261
 protein coding gene Chr4:61565937-61625681 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028156
 protein coding gene Chr4:68715334-68779177 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028805
 protein coding gene Chr4:60796553-60856288 (-)
PWK/PhJ MGP_PWKPhJ_G0027210
 protein coding gene Chr4:57393739-57452333 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027039
 protein coding gene Chr4:58236521-58300648 (-)
WSB/EiJ MGP_WSBEiJ_G0027563
 protein coding gene Chr4:60779598-60840166 (-)



Homology
more
  • Human Ortholog
    FKBP15, FKBP prolyl isomerase family member 15
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FKBP15, FKBP prolyl isomerase family member 15
  • Synonyms
    FKBP133, KIAA0674, PPP1R76
  • Links
    NCBI Gene ID: 23307
    neXtProt AC: NX_Q5T1M5
    UniProt: Q5T1M5

  • Chr Location
    9q32; chr9:113161006-113221458 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    793
  • Tissues
    31
  • cDNA Data
    97
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066151 Ensembl Gene Model | MGI Sequence Detail 60207 C57BL/6J ±  kb
transcript ENSMUST00000084527 Ensembl | MGI Sequence Detail 4264 Not Applicable  
polypeptide ENSMUSP00000081575 Ensembl | MGI Sequence Detail 1216 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000007535 FK506-binding protein 15
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
    IPR046357 Peptidyl-prolyl cis-trans isomerase domain superfamily
  • GlyGen
    Q6P9Q6 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 99
    Genomic 2
    cDNA 97

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140638
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:240360 Tyrrell BJ, et al., Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour. Pigment Cell Melanoma Res. 2016 Sep;29(5):559-71
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory