Paqr9 MGI Mouse Gene Detail - MGI:1922802 - progestin and adipoQ receptor family member IX

Symbol

Paqr9
Name

progestin and adipoQ receptor family member IX
Synonyms

1700020G04Rik, C730029A08Rik

Feature Type

protein coding gene
IDs

MGI:1922802
NCBI Gene: 75552
Alliance

gene page
Transcription Start Sites

18 TSS

Sequence Map

Chr9:95441710-95450076 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, Syntenic
Mapping Data

1 experiment

SNPs within 2kb

290 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922802	protein coding gene	Chr9:95441687-95450076 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035135	protein coding gene	Chr9:96683736-96692098 (+)
A/J	MGP_AJ_G0035116	protein coding gene	Chr9:93334505-93342869 (+)
AKR/J	MGP_AKRJ_G0035048	protein coding gene	Chr9:95589700-95598065 (+)
BALB/cJ	MGP_BALBcJ_G0035109	protein coding gene	Chr9:93022545-93030909 (+)
C3H/HeJ	MGP_C3HHeJ_G0034819	protein coding gene	Chr9:96030394-96038758 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035629	protein coding gene	Chr9:99454817-99463190 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032531	protein coding gene	Chr9:91156882-91164791 (+)
CAST/EiJ	MGP_CASTEiJ_G0034131	protein coding gene	Chr9:95747973-95756333 (+)
CBA/J	MGP_CBAJ_G0034787	protein coding gene	Chr9:102903195-102911559 (+)
DBA/2J	MGP_DBA2J_G0034949	protein coding gene	Chr9:92861506-92869870 (+)
FVB/NJ	MGP_FVBNJ_G0034897	protein coding gene	Chr9:91711944-91720308 (+)
LP/J	MGP_LPJ_G0035028	protein coding gene	Chr9:96948379-96956743 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034936	protein coding gene	Chr9:104909966-104918332 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035651	protein coding gene	Chr9:95814560-95822927 (+)
PWK/PhJ	MGP_PWKPhJ_G0033838	protein coding gene	Chr9:93005338-93013710 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033673	protein coding gene	Chr9:95815331-95823662 (+)
WSB/EiJ	MGP_WSBEiJ_G0034251	protein coding gene	Chr9:95678533-95686898 (+)

Human Ortholog

PAQR9, progestin and adipoQ receptor family member 9

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PAQR9, progestin and adipoQ receptor family member 9
Synonyms

BLNC1
Links

HGNC:30131

NCBI Gene ID: 344838

neXtProt AC: NX_Q6ZVX9

UniProt: Q6ZVX9
Chr Location

3q23; chr3:142949164-142964008 (-) GRCh38

MGI Vertebrate Homology

Paqr9 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PAQR9
Gene Tree

Paqr9

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

1
Endonuclease-mediated

2
Targeted

2
Genomic Mutations

1 involving Paqr9
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

18 strains or lines available

Homozygous knockout reduces susceptibility to induced weight gain or obesity.

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All GO Annotations

3
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

759
Tissues

14
cDNA Data

39
Literature Summary

5

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase paqr9

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All Sequences

36
RefSeq

2
UniProt

1
CCDS

CCDS23409.1

Ensembl

ENSMUSG00000064225 (Evidence)
NCBI Gene

75552

			Length	Strain/Species	Flank
genomic	ENSMUSG00000064225	Ensembl Gene Model \| MGI Sequence Detail	8367	C57BL/6J	± kb
transcript	ENSMUST00000079597	Ensembl \| MGI Sequence Detail	8367	Not Applicable
polypeptide	ENSMUSP00000078547	Ensembl \| MGI Sequence Detail	375	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000030542 membrane progestin receptor epsilon

(term hierarchy)
InterPro Domains

IPR004254 AdipoR/Haemolysin-III-related

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All nucleic 41

cDNA 39

Primer pair 2

Microarray probesets 7

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MGI:2445056

Summaries

All 36

Developmental Gene Expression 5

Gene Ontology 3

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:340697 Li Z, et al., PAQR9 regulates glucose homeostasis in diabetic mice and modulates insulin secretion in beta cells in vitro under stress conditions. Mol Cell Endocrinol. 2023 Jul 25;575:112032

TSS for Paqr9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr86553	Chr9:95441132-95441149 (+)	-569 bp
Tssr86554	Chr9:95441172-95441201 (+)	-523 bp
Tssr86555	Chr9:95441202-95441214 (+)	-502 bp
Tssr86556	Chr9:95441373-95441384 (+)	-331 bp
Tssr86557	Chr9:95441402-95441420 (+)	-299 bp
Tssr86558	Chr9:95441424-95441444 (+)	-276 bp
Tssr86559	Chr9:95441586-95441597 (+)	-118 bp
Tssr86560	Chr9:95441624-95441636 (+)	-80 bp
Tssr86561	Chr9:95441652-95441705 (+)	-31 bp
Tssr86562	Chr9:95441714-95441758 (+)	26 bp
Tssr86563	Chr9:95441968-95442013 (+)	281 bp
Tssr86564	Chr9:95442089-95442098 (+)	384 bp
Tssr86565	Chr9:95442450-95442483 (+)	757 bp
Tssr86566	Chr9:95442486-95442501 (+)	784 bp
Tssr86567	Chr9:95443144-95443160 (+)	1,442 bp
Tssr86568	Chr9:95443612-95443615 (+)	1,904 bp
Tssr86569	Chr9:95445807-95445810 (+)	4,099 bp
Tssr86570	Chr9:95446521-95446525 (+)	4,813 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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