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Arl4c Gene Detail
Summary
  • Symbol
    Arl4c
  • Name
    ADP-ribosylation factor-like 4C
  • Synonyms
    A630084M22Rik, Arl7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445172
    NCBI Gene: 320982
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88625947-88629913 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 44.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445172
 protein coding gene Chr1:88600847-88629943 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016288
 protein coding gene Chr1:90108088-90138326 (-)
A/J MGP_AJ_G0016269
 protein coding gene Chr1:86873764-86904410 (-)
AKR/J MGP_AKRJ_G0016230
 protein coding gene Chr1:89442427-89473084 (-)
BALB/cJ MGP_BALBcJ_G0016225
 protein coding gene Chr1:87010616-87039903 (-)
C3H/HeJ MGP_C3HHeJ_G0016054
 protein coding gene Chr1:89652327-89683294 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016684
 protein coding gene Chr1:93596257-93641385 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014402
 protein coding gene Chr1:81186589-81190571 (-)
CAST/EiJ MGP_CASTEiJ_G0015639
 protein coding gene Chr1:88966837-88970840 (-)
CBA/J MGP_CBAJ_G0016030
 protein coding gene Chr1:96572596-96611018 (-)
DBA/2J MGP_DBA2J_G0016133
 protein coding gene Chr1:86099562-86129154 (-)
FVB/NJ MGP_FVBNJ_G0016132
 protein coding gene Chr1:85128376-85159999 (-)
LP/J MGP_LPJ_G0016204
 protein coding gene Chr1:91250254-91281725 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016157
 protein coding gene Chr1:99938916-99970259 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016724
 protein coding gene Chr1:89470888-89501362 (-)
PWK/PhJ MGP_PWKPhJ_G0015423
 protein coding gene Chr1:85487308-85517003 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015206
 protein coding gene Chr1:88372907-88376865 (-)
WSB/EiJ MGP_WSBEiJ_G0015697
 protein coding gene Chr1:89168189-89198562 (-)



Homology
more
  • Human Ortholog
    ARL4C, ARF like GTPase 4C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL4C, ARF like GTPase 4C
  • Synonyms
    ARL7, LAK
  • Links
    NCBI Gene ID: 10123
    neXtProt AC: NX_P56559
    UniProt: P56559

  • Chr Location
    2q37.1; chr2:234493041-234497081 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Arl4c
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    870
  • Tissues
    38
  • cDNA Data
    9
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320982 NCBI Gene Model | MGI Sequence Detail 3967 C57BL/6J ±  kb
transcript NM_177305 RefSeq | MGI Sequence Detail 3967 C57BL/6  
polypeptide P61208 UniProt | EBI | MGI Sequence Detail 192 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:343161 Truong TTK, et al., Arl4c is involved in tooth germ development through osteoblastic/ameloblastic differentiation. Biochem Biophys Res Commun. 2023 Oct 30;679:167-174
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory