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Bms1 Gene Detail
Summary
  • Symbol
    Bms1
  • Name
    BMS1, ribosome biogenesis factor
  • Synonyms
    Bms1l, mKIAA0187
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446132
    NCBI Gene: 213895
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:118360342-118396435 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 55.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446132
 protein coding gene Chr6:118360342-118396772 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031185
 protein coding gene Chr6:121130999-121175329 (-)
A/J MGP_AJ_G0031154
 protein coding gene Chr6:116497018-116535348 (-)
AKR/J MGP_AKRJ_G0031085
 protein coding gene Chr6:119626523-119665521 (-)
BALB/cJ MGP_BALBcJ_G0031165
 protein coding gene Chr6:116274623-116310889 (-)
C3H/HeJ MGP_C3HHeJ_G0030544
 protein coding gene Chr6:64632825-64670130 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031623
 protein coding gene Chr6:124245037-124286988 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028785
 protein coding gene Chr6:113416957-113453041 (-)
CAST/EiJ MGP_CASTEiJ_G0030272
 protein coding gene Chr6:120030867-120067823 (-)
CBA/J MGP_CBAJ_G0030848
 protein coding gene Chr6:129144406-129196870 (-)
DBA/2J MGP_DBA2J_G0031004
 protein coding gene Chr6:115395789-115432474 (-)
FVB/NJ MGP_FVBNJ_G0030956
 protein coding gene Chr6:114527940-114565067 (-)
LP/J MGP_LPJ_G0031083
 protein coding gene Chr6:121165201-121203573 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030990
 protein coding gene Chr6:133240803-133283725 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031652
 protein coding gene Chr6:119656725-119693495 (-)
PWK/PhJ MGP_PWKPhJ_G0029987
 protein coding gene Chr6:114414111-114450415 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029816
 protein coding gene Chr6:118365470-118403226 (-)
WSB/EiJ MGP_WSBEiJ_G0030355
 protein coding gene Chr6:119924258-119962521 (-)



Homology
more
  • Human Ortholog
    BMS1, BMS1 ribosome biogenesis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BMS1, BMS1 ribosome biogenesis factor
  • Synonyms
    ACC, BMS1L
  • Links
    NCBI Gene ID: 9790
    neXtProt AC: NX_Q14692
    UniProt: Q14692

  • Chr Location
    10q11.21; chr10:42782795-42834937 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human BMS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    206
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030138 Ensembl Gene Model | MGI Sequence Detail 36094 C57BL/6J ±  kb
    transcript ENSMUST00000032237 Ensembl | MGI Sequence Detail 4345 Not Applicable  
    polypeptide ENSMUSP00000032237 Ensembl | MGI Sequence Detail 1284 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR012948 AARP2CN
      IPR030387 Bms1/Tsr1-type G domain
      IPR027417 P-loop containing nucleoside triphosphate hydrolase
      IPR037875 Ribosome biogenesis protein Bms1, N-terminal
      IPR039761 Ribosome biogenesis protein Bms1/Tsr1
      IPR007034 Ribosome biogenesis protein BMS1/TSR1, C-terminal
    • GlyGen
      Q6PGF5 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 206
      cDNA 206

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1353661, MGI:2141564, MGI:2141589, MGI:2141723
    References
    more
    • Summaries
      All 34
      Gene Ontology 2
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory