About   Help   FAQ
Samd11 Gene Detail
Summary
  • Symbol
    Samd11
  • Name
    sterile alpha motif domain containing 11
  • Synonyms
    MGC:38976, mr-s
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446220
    NCBI Gene: 231004
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:156331423-156340717 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    609 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446220
 protein coding gene Chr4:156331423-156342409 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029254
 protein coding gene Chr4:160619461-160628390 (-)
A/J MGP_AJ_G0029219
 protein coding gene Chr4:153853593-153863429 (-)
AKR/J MGP_AKRJ_G0029167
 protein coding gene Chr4:158046776-158056762 (-)
BALB/cJ MGP_BALBcJ_G0029235
 protein coding gene Chr4:154329846-154338966 (-)
C3H/HeJ MGP_C3HHeJ_G0028956
 protein coding gene Chr4:158622601-158632726 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029684
 protein coding gene Chr4:166321973-166336711 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026927
 protein coding gene Chr4:146130424-146139548 (-)
CAST/EiJ MGP_CASTEiJ_G0028368
 protein coding gene Chr4:156039789-156056265 (-)
CBA/J MGP_CBAJ_G0028918
 protein coding gene Chr4:171387564-171399750 (-)
DBA/2J MGP_DBA2J_G0029067
 protein coding gene Chr4:153873417-153882512 (-)
FVB/NJ MGP_FVBNJ_G0029030
 protein coding gene Chr4:153123493-153133023 (-)
LP/J MGP_LPJ_G0029157
 protein coding gene Chr4:160582445-160591602 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029057
 protein coding gene Chr4:174146509-174157233 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029716
 protein coding gene Chr4:158677157-158686097 (-)
PWK/PhJ MGP_PWKPhJ_G0028088
 protein coding gene Chr4:150016136-150027331 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027922
 protein coding gene Chr4:152926354-152933832 (-)
WSB/EiJ MGP_WSBEiJ_G0028448
 protein coding gene Chr4:158860695-158871581 (-)



Homology
more
  • Human Ortholog
    SAMD11, sterile alpha motif domain containing 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAMD11, sterile alpha motif domain containing 11
  • Synonyms
    MRS
  • Links
    NCBI Gene ID: 148398
    neXtProt AC: NX_Q96NU1
    UniProt: Q96NU1

  • Chr Location
    1p36.33; chr1:923923-944575 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotypes from multigenic genotypes
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele are viable and show no gross abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    33
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096351 Ensembl Gene Model | MGI Sequence Detail 9295 C57BL/6J ±  kb
transcript ENSMUST00000179919 Ensembl | MGI Sequence Detail 2610 Not Applicable  
polypeptide ENSMUSP00000136611 Ensembl | MGI Sequence Detail 552 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000014441 sterile alpha motif domain-containing protein 11
    (term hierarchy)
  • InterPro Domains
    IPR050548 Polycomb group and chromatin remodeling factors
    IPR001660 Sterile alpha motif domain
    IPR013761 Sterile alpha motif/pointed domain superfamily
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory