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Ntm Gene Detail
Summary
  • Symbol
    Ntm
  • Name
    neurotrimin
  • Synonyms
    6230410L23Rik, B230210G24Rik, Hnt
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446259
    NCBI Gene: 235106
  • Alliance
    gene page
  • Transcription Start Sites
    29 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:28906046-29874437 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 14.38 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25262 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446259
 protein coding gene Chr9:28906045-29874565 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034511
 protein coding gene Chr9:26547710-27561539 (-)
A/J MGP_AJ_G0034489
 protein coding gene Chr9:25930222-26905781 (-)
AKR/J MGP_AKRJ_G0034415
 protein coding gene Chr9:26447841-27454002 (-)
BALB/cJ MGP_BALBcJ_G0034480
 protein coding gene Chr9:25836812-26831246 (-)
C3H/HeJ MGP_C3HHeJ_G0034192
 protein coding gene Chr9:26817532-27810871 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035001
 protein coding gene Chr9:27519723-28534289 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031931
 protein coding gene Chr9:24815817-25774215 (-)
CAST/EiJ MGP_CASTEiJ_G0033515
 protein coding gene Chr9:26660374-27675770 (-)
CBA/J MGP_CBAJ_G0034165
 protein coding gene Chr9:28417638-29449677 (-)
DBA/2J MGP_DBA2J_G0034323
 protein coding gene Chr9:25947324-26921209 (-)
FVB/NJ MGP_FVBNJ_G0034266
 protein coding gene Chr9:25375178-26344965 (-)
LP/J MGP_LPJ_G0034409
 protein coding gene Chr9:26722702-27742581 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034310
 protein coding gene Chr9:30121957-31159465 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035021
 protein coding gene Chr9:26465343-27470416 (-)
PWK/PhJ MGP_PWKPhJ_G0033220
 protein coding gene Chr9:25881320-26860822 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033054
 protein coding gene Chr9:26537922-27549802 (-)
WSB/EiJ MGP_WSBEiJ_G0033630
 protein coding gene Chr9:26208034-27194925 (-)



Homology
more
  • Human Ortholog
    NTM, neurotrimin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NTM, neurotrimin
  • Synonyms
    CEPU-1, HNT, IGLON2, NTRI
  • Links
    NCBI Gene ID: 50863
    neXtProt AC: NX_Q9P121
    UniProt: Q9P121

  • Chr Location
    11q25; chr11:131370478-132336822 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired behavioral response to amphetamine and a deficit in emotional learning in the active avoidance ask. Homozygous KO has no cardiac effect.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1271
  • Tissues
    235
  • cDNA Data
    19
  • Literature Summary
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059974 Ensembl Gene Model | MGI Sequence Detail 968392 C57BL/6J ±  kb
    transcript ENSMUST00000075069 Ensembl | MGI Sequence Detail 3022 Not Applicable  
    polypeptide ENSMUSP00000074578 Ensembl | MGI Sequence Detail 344 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 19
      Primer pair 1
      Other 2

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1915534, MGI:1923369, MGI:2143451
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 16
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:357284 Lo Giudice Q, et al., Developmental emergence of first- and higher-order thalamic neuron molecular identities. Development. 2024 Sep 15;151(18)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory