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Wdr24 Gene Detail
Summary
  • Symbol
    Wdr24
  • Name
    WD repeat domain 24
  • Synonyms
    MGC:47001
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446285
    NCBI Gene: 268933
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26042601-26047704 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446285
 protein coding gene Chr17:26042601-26047704 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023371
 protein coding gene Chr17:24920958-24926063 (+)
A/J MGP_AJ_G0023330
 protein coding gene Chr17:24196532-24201635 (+)
AKR/J MGP_AKRJ_G0023296
 protein coding gene Chr17:24302096-24307196 (+)
BALB/cJ MGP_BALBcJ_G0023335
 protein coding gene Chr17:24424605-24429706 (+)
C3H/HeJ MGP_C3HHeJ_G0023095
 protein coding gene Chr17:24685703-24690805 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023777
 protein coding gene Chr17:25973991-25979120 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021253
 protein coding gene Chr17:21658097-21663194 (+)
CAST/EiJ MGP_CASTEiJ_G0022597
 protein coding gene Chr17:24571067-24576167 (+)
CBA/J MGP_CBAJ_G0023070
 protein coding gene Chr17:26885697-26890800 (+)
DBA/2J MGP_DBA2J_G0023200
 protein coding gene Chr17:23798551-23804309 (+)
FVB/NJ MGP_FVBNJ_G0023170
 protein coding gene Chr17:23539355-23544459 (+)
LP/J MGP_LPJ_G0023277
 protein coding gene Chr17:25219067-25226720 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023189
 protein coding gene Chr17:26498052-26503155 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023817
 protein coding gene Chr17:24621619-24626721 (+)
PWK/PhJ MGP_PWKPhJ_G0022346
 protein coding gene Chr17:22560532-22565627 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022164
 protein coding gene Chr17:22695421-22700514 (+)
WSB/EiJ MGP_WSBEiJ_G0022660
 protein coding gene Chr17:24672334-24677433 (+)



Homology
more
  • Human Ortholog
    WDR24, WD repeat domain 24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR24, WD repeat domain 24
  • Synonyms
    C16orf21, JFP7
  • Links
    NCBI Gene ID: 84219
    neXtProt AC: NX_Q96S15
    UniProt: Q96S15

  • Chr Location
    16p13.3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 3 alleles in 3 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygosity for a phosphomimetic mutation at Ser155 is early embryonic lethal. Homozygosity for a phosphoblocking mutation at Ser155 affects glucose sensing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    14
  • cDNA Data
    42
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 268933 NCBI Gene Model | MGI Sequence Detail 5104 C57BL/6J ±  kb
    transcript NM_173741 RefSeq | MGI Sequence Detail 3099 C57BL/6  
    polypeptide Q8CFJ9 UniProt | EBI | MGI Sequence Detail 790 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 42

      Microarray probesets 2
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory