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Map3k7cl Gene Detail
Summary
  • Symbol
    Map3k7cl
  • Name
    Map3k7 C-terminal like
  • Synonyms
    ORF63
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446584
    NCBI Gene: 224419
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:87350218-87392224 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 49.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1703 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446584
protein coding gene Chr16:87350208-87392224 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022980
protein coding gene Chr16:88276359-88322786 (+)
A/J MGP_AJ_G0022948
protein coding gene Chr16:84204495-84248460 (+)
AKR/J MGP_AKRJ_G0022918
protein coding gene Chr16:86772192-86815273 (+)
BALB/cJ MGP_BALBcJ_G0022950
protein coding gene Chr16:84733276-84776740 (+)
C3H/HeJ MGP_C3HHeJ_G0022712
protein coding gene Chr16:87331758-87376318 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023397
protein coding gene Chr16:91141928-91185262 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020901
protein coding gene Chr16:82059141-82097324 (+)
CAST/EiJ MGP_CASTEiJ_G0022234
protein coding gene Chr16:87709020-87754412 (+)
CBA/J MGP_CBAJ_G0022681
protein coding gene Chr16:95052612-95101305 (+)
DBA/2J MGP_DBA2J_G0022815
protein coding gene Chr16:84129884-84172021 (+)
FVB/NJ MGP_FVBNJ_G0022790
protein coding gene Chr16:83235590-83279556 (+)
LP/J MGP_LPJ_G0022884
protein coding gene Chr16:87959621-88008047 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022809
protein coding gene Chr16:99605655-99658477 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023415
protein coding gene Chr16:87241980-87286674 (+)
PWK/PhJ MGP_PWKPhJ_G0021977
protein coding gene Chr16:84245198-84290743 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021807
protein coding gene Chr16:86769428-86812413 (+)
WSB/EiJ MGP_WSBEiJ_G0022282
protein coding gene Chr16:87469656-87517183 (+)



Homology
more
  • Human Ortholog
    MAP3K7CL, MAP3K7 C-terminal like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAP3K7CL, MAP3K7 C-terminal like
  • Synonyms
    C21orf7, HC21ORF7, TAK1L, TAKL, TAKL-1, TAKL-2, TAKL-4
  • Links
    NCBI Gene ID: 56911
    neXtProt AC: NX_P57077
    UniProt: P57077

  • Chr Location
    21q21.3; chr21:29077114-29175889 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025610 Ensembl Gene Model | MGI Sequence Detail 42007 C57BL/6J ±  kb
transcript ENSMUST00000026700 Ensembl | MGI Sequence Detail 1652 Not Applicable  
polypeptide ENSMUSP00000026700 Ensembl | MGI Sequence Detail 142 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Diseases 1
    Phenotypes 20
  • Earliest
    J:76842 Reymond A, et al., From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Genomics. 2001 Nov;78(1-2):46-54
  • Latest
    J:345472 Lana-Elola E, et al., Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Sci Transl Med. 2024 Jan 24;16(731):eadd6883

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory