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Cmtm1 Gene Detail
Summary
  • Symbol
    Cmtm1
  • Name
    CKLF-like MARVEL transmembrane domain containing 1
  • Synonyms
    CHLFH1a, CKLFH1, Cklfsf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447159
    NCBI Gene: 100504164
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:105020174-105036777 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    503 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447159
 protein coding gene Chr8:105019555-105036777 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CMTM1, CKLF like MARVEL transmembrane domain containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CMTM1, CKLF like MARVEL transmembrane domain containing 1
  • Synonyms
    CKLFH, CKLFH1, CKLFSF1
  • Links
    NCBI Gene ID: 113540
    neXtProt AC: NX_Q8IZ96
    UniProt: Q8IZ96

  • Chr Location
    16q21; chr16:66566393-66579137 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Mice homozygous for a knock-out allele exhibit normal male spermatozoa and fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100504164 NCBI Gene Model | MGI Sequence Detail 16604 C57BL/6J ±  kb
transcript NM_181990 RefSeq | MGI Sequence Detail 1130 C57BL/6  
polypeptide NP_871790 RefSeq | MGI Sequence Detail 303 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:84235 Han W, et al., Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Genomics. 2003 Jun;81(6):609-17
  • Latest
    J:266476 Fujihara Y, et al., Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice. J Cell Sci. 2018 Oct 8;131(19):jcs221481
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory