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Cmtm8 Gene Detail
Summary
  • Symbol
    Cmtm8
  • Name
    CKLF-like MARVEL transmembrane domain containing 8
  • Synonyms
    2700018N07Rik, Cklfsf8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447167
    NCBI Gene: 70031
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:114618411-114673220 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 65.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2096 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447167
 protein coding gene Chr9:114618411-114673224 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035395
 protein coding gene Chr9:117251076-117318884 (-)
A/J MGP_AJ_G0035375
 protein coding gene Chr9:112956321-113014034 (-)
AKR/J MGP_AKRJ_G0035308
 protein coding gene Chr9:115830770-115887691 (-)
BALB/cJ MGP_BALBcJ_G0035371
 protein coding gene Chr9:112762389-112819494 (-)
C3H/HeJ MGP_C3HHeJ_G0035079
 protein coding gene Chr9:116329532-116389560 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035894
 protein coding gene Chr9:120468981-120525498 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032777
 protein coding gene Chr9:110253411-110309093 (-)
CAST/EiJ MGP_CASTEiJ_G0034384
 protein coding gene Chr9:116196019-116256901 (-)
CBA/J MGP_CBAJ_G0035046
 protein coding gene Chr9:124977967-125037417 (-)
DBA/2J MGP_DBA2J_G0035205
 protein coding gene Chr9:112428052-112483658 (-)
FVB/NJ MGP_FVBNJ_G0035152
 protein coding gene Chr9:111255686-111316176 (-)
LP/J MGP_LPJ_G0035284
 protein coding gene Chr9:117590937-117658183 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035193
 protein coding gene Chr9:126196251-126254599 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035913
 protein coding gene Chr9:116205163-116262976 (-)
PWK/PhJ MGP_PWKPhJ_G0034090
 protein coding gene Chr9:112737922-112802210 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033924
 protein coding gene Chr9:116248799-116315287 (-)
WSB/EiJ MGP_WSBEiJ_G0034504
 protein coding gene Chr9:116088647-116154172 (-)



Homology
more
  • Human Ortholog
    CMTM8, CKLF like MARVEL transmembrane domain containing 8
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CMTM8, CKLF like MARVEL transmembrane domain containing 8
  • Synonyms
    CKLFSF8, CKLFSF8-V2
  • Links
    NCBI Gene ID: 152189
    neXtProt AC: NX_Q8IZV2
    UniProt: Q8IZV2

  • Chr Location
    3p22.3; chr3:32238192-32370321 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    786
  • Tissues
    19
  • cDNA Data
    39
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70031 NCBI Gene Model | MGI Sequence Detail 54810 C57BL/6J ±  kb
transcript NM_027294 RefSeq | MGI Sequence Detail 1064 C57BL/6  
polypeptide Q9CZR4 UniProt | EBI | MGI Sequence Detail 173 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032075 CKLF-like MARVEL transmembrane domain-containing protein 8
    (term hierarchy)
  • InterPro Domains
    IPR008253 Marvel domain
    IPR050578 MARVEL domain-containing and chemokine-like factor proteins
    IPR013295 Myelin and lymphocyte (MAL) protein
Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917281, MGI:2142922
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory