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Yeats2 Gene Detail
Summary
  • Symbol
    Yeats2
  • Name
    YEATS domain containing 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447762
    NCBI Gene: 208146
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:19959813-20051323 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 12.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2177 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447762
 protein coding gene Chr16:19959803-20051323 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022599
 protein coding gene Chr16:16612956-16704517 (+)
AKR/J MGP_AKRJ_G0022574
 protein coding gene Chr16:17247815-17342203 (+)
BALB/cJ MGP_BALBcJ_G0022603
 protein coding gene Chr16:16759986-16851458 (+)
C3H/HeJ MGP_C3HHeJ_G0022368
 protein coding gene Chr16:17410159-17503882 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023054
 protein coding gene Chr16:17784659-17876435 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020571
 protein coding gene Chr16:17300786-17396134 (+)
CAST/EiJ MGP_CASTEiJ_G0021898
 protein coding gene Chr16:17389151-17481345 (+)
CBA/J MGP_CBAJ_G0022340
 protein coding gene Chr16:18507796-18604337 (+)
DBA/2J MGP_DBA2J_G0022472
 protein coding gene Chr16:16542350-16634455 (+)
FVB/NJ MGP_FVBNJ_G0022447
 protein coding gene Chr16:16572409-16665996 (+)
LP/J MGP_LPJ_G0022539
 protein coding gene Chr16:17189146-17284193 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022467
 protein coding gene Chr16:18206124-18311756 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023065
 protein coding gene Chr16:17198044-17292930 (+)
PWK/PhJ MGP_PWKPhJ_G0021639
 protein coding gene Chr16:16786562-16880715 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021468
 protein coding gene Chr16:16999809-17094471 (+)
WSB/EiJ MGP_WSBEiJ_G0021942
 protein coding gene Chr16:17196152-17291566 (+)



Homology
more
  • Human Ortholog
    YEATS2, YEATS domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    YEATS2, YEATS domain containing 2
  • Synonyms
    FAME4
  • Links
    NCBI Gene ID: 55689
    neXtProt AC: NX_Q9ULM3
    UniProt: Q9ULM3

  • Chr Location
    3q27.1; chr3:183697797-183812624 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human YEATS2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    42
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    134
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041215 Ensembl Gene Model | MGI Sequence Detail 91511 C57BL/6J ±  kb
transcript ENSMUST00000115560 Ensembl | MGI Sequence Detail 6112 Not Applicable  
polypeptide ENSMUSP00000111222 Ensembl | MGI Sequence Detail 1407 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 134
    cDNA 134

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory