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Npepl1 Gene Detail
Summary
  • Symbol
    Npepl1
  • Name
    aminopeptidase-like 1
  • Synonyms
    mKIAA1974
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448523
    NCBI Gene: 228961
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:173951904-173964495 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 97.87 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448523
 protein coding gene Chr2:173951904-173964863 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026963
 protein coding gene Chr2:180446572-180460346 (+)
A/J MGP_AJ_G0026930
 protein coding gene Chr2:172844079-172856803 (+)
AKR/J MGP_AKRJ_G0026901
 protein coding gene Chr2:178049014-178061746 (+)
BALB/cJ MGP_BALBcJ_G0026939
 protein coding gene Chr2:173234800-173247532 (+)
C3H/HeJ MGP_C3HHeJ_G0026681
 protein coding gene Chr2:178433366-178446087 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027386
 protein coding gene Chr2:185637763-185650484 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024755
 protein coding gene Chr2:166086209-166099001 (+)
CAST/EiJ MGP_CASTEiJ_G0026140
 protein coding gene Chr2:179160741-179173488 (+)
CBA/J MGP_CBAJ_G0026658
 protein coding gene Chr2:192558732-192571464 (+)
DBA/2J MGP_DBA2J_G0026796
 protein coding gene Chr2:171938774-171951495 (+)
FVB/NJ MGP_FVBNJ_G0026762
 protein coding gene Chr2:170561889-170574621 (+)
LP/J MGP_LPJ_G0026897
 protein coding gene Chr2:180362851-180375575 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026781
 protein coding gene Chr2:195459673-195472405 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027443
 protein coding gene Chr2:178076469-178089201 (+)
PWK/PhJ MGP_PWKPhJ_G0025876
 protein coding gene Chr2:171751623-171764434 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025676
 protein coding gene Chr2:177112393-177126656 (+)
WSB/EiJ MGP_WSBEiJ_G0026212
 protein coding gene Chr2:179044049-179056789 (+)



Homology
more
  • Human Ortholog
    NPEPL1, aminopeptidase like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NPEPL1, aminopeptidase like 1
  • Synonyms
    bA261P9.2
  • Links
    NCBI Gene ID: 79716
    neXtProt AC: NX_Q8NDH3
    UniProt: Q8NDH3

  • Chr Location
    20q13.32; chr20:58689131-58719238 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    81
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228961 NCBI Gene Model | MGI Sequence Detail 12592 C57BL/6J ±  kb
transcript NM_001378793 RefSeq | MGI Sequence Detail 2112 C57BL/6  
polypeptide Q6NSR8 UniProt | EBI | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139519
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory