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Atcay Gene Detail
Summary
  • Symbol
    Atcay
  • Name
    ataxia, cerebellar, Cayman type
  • Synonyms
    3322401A10Rik, BNIP-H, ji
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448730
    NCBI Gene: 16467
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81040342-81066667 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    673 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448730
 protein coding gene Chr10:81040338-81067037 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017543
 protein coding gene Chr10:81904350-81931973 (-)
A/J MGP_AJ_G0017521
 protein coding gene Chr10:79004893-79033931 (-)
AKR/J MGP_AKRJ_G0017482
 protein coding gene Chr10:81181004-81207566 (-)
BALB/cJ MGP_BALBcJ_G0017483
 protein coding gene Chr10:79224196-79252428 (-)
C3H/HeJ MGP_C3HHeJ_G0017306
 protein coding gene Chr10:81269549-81299930 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017937
 protein coding gene Chr10:84719908-84749015 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015626
 protein coding gene Chr10:75203564-75231167 (-)
CAST/EiJ MGP_CASTEiJ_G0016873
 protein coding gene Chr10:81502339-81529761 (-)
CBA/J MGP_CBAJ_G0017278
 protein coding gene Chr10:88016517-88054290 (-)
DBA/2J MGP_DBA2J_G0017384
 protein coding gene Chr10:78212797-78239181 (-)
FVB/NJ MGP_FVBNJ_G0017378
 protein coding gene Chr10:77453242-77483366 (-)
LP/J MGP_LPJ_G0017455
 protein coding gene Chr10:82356567-82387111 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017404
 protein coding gene Chr10:89880858-89910558 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017978
 protein coding gene Chr10:81169435-81209777 (-)
PWK/PhJ MGP_PWKPhJ_G0016654
 protein coding gene Chr10:78103661-78131093 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016444
 protein coding gene Chr10:80126353-80157922 (-)
WSB/EiJ MGP_WSBEiJ_G0016933
 protein coding gene Chr10:81209101-81239072 (-)



Homology
more
  • Human Ortholog
    ATCAY, ATCAY kinesin light chain interacting caytaxin
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATCAY, ATCAY kinesin light chain interacting caytaxin
  • Synonyms
    BNIP-H, CLAC
  • Links
    NCBI Gene ID: 85300
    neXtProt AC: NX_Q86WG3
    UniProt: Q86WG3

  • Chr Location
    19p13.3
Human Diseases
more
  • Diseases
    1 with Atcay mouse models; 2 with human ATCAY associations

Human Disease Mouse Models
      
IDs
 View 3 models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    3 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 6 alleles in 6 genetic backgrounds
    2 phenotypes from multigenic genotypes
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutants homozygous for a severe allele show progressive impaired coordination and seizures beginning by 10-16 days of age and die by 4 weeks of age. Homozygotes for milder alleles have abnormal gait, slightly diminished body size and reduced male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    914
  • Tissues
    32
  • cDNA Data
    49
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034958 Ensembl Gene Model | MGI Sequence Detail 26326 C57BL/6J ±  kb
    transcript ENSMUST00000047408 Ensembl | MGI Sequence Detail 3736 Not Applicable  
    polypeptide ENSMUSP00000036721 Ensembl | MGI Sequence Detail 372 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 50
      cDNA 50

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-10693, MGD-MRK-11529, MGI:2143893, MGI:2442176, MGI:96640
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 7
      Phenotypes 23
    • Earliest
      J:300 Snell GD, Linkage of jittery and waltzing in the mouse. J Hered. 1945;36(9):279-80
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory