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Cndp1 Gene Detail
Summary
  • Symbol
    Cndp1
  • Name
    carnosine dipeptidase 1
  • Synonyms
    Cn1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2451097
    NCBI Gene: 338403
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:84628634-84668220 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 57.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1366 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2451097
 protein coding gene Chr18:84628509-84668359 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024607
 protein coding gene Chr18:85773001-85812355 (-)
A/J MGP_AJ_G0024574
 protein coding gene Chr18:81999355-82039810 (-)
AKR/J MGP_AKRJ_G0024545
 protein coding gene Chr18:84433458-84477128 (-)
BALB/cJ MGP_BALBcJ_G0024572
 protein coding gene Chr18:82194897-82234856 (-)
C3H/HeJ MGP_C3HHeJ_G0024341
 protein coding gene Chr18:84548382-84587626 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025019
 protein coding gene Chr18:87905228-87946532 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022450
 protein coding gene Chr18:80696772-80738056 (-)
CAST/EiJ MGP_CASTEiJ_G0023814
 protein coding gene Chr18:84910159-84951612 (-)
CBA/J MGP_CBAJ_G0024311
 protein coding gene Chr18:91056647-91096004 (-)
DBA/2J MGP_DBA2J_G0024441
 protein coding gene Chr18:81516074-81557420 (-)
FVB/NJ MGP_FVBNJ_G0024407
 protein coding gene Chr18:80852397-80892040 (-)
LP/J MGP_LPJ_G0024525
 protein coding gene Chr18:85566414-85608797 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024437
 protein coding gene Chr18:92286056-92333865 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025068
 protein coding gene Chr18:84644520-84690120 (-)
PWK/PhJ MGP_PWKPhJ_G0023559
 protein coding gene Chr18:81908550-81952824 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023365
 protein coding gene Chr18:84680130-84724665 (-)
WSB/EiJ MGP_WSBEiJ_G0023876
 protein coding gene Chr18:84604255-84648993 (-)



Homology
more
  • Human Ortholog
    CNDP1, carnosine dipeptidase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNDP1, carnosine dipeptidase 1
  • Synonyms
    CN1, CPGL2, HsT2308
  • Links
    NCBI Gene ID: 84735
    neXtProt AC: NX_Q96KN2
    UniProt: Q96KN2

  • Chr Location
    18q22.3; chr18:74534500-74587212 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CNDP1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    809
  • Tissues
    95
  • cDNA Data
    11
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056162 Ensembl Gene Model | MGI Sequence Detail 39587 C57BL/6J ±  kb
transcript ENSMUST00000070139 Ensembl | MGI Sequence Detail 2829 Not Applicable  
polypeptide ENSMUSP00000069699 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147261
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:91725 Tarozzo G, et al., Prenatal differentiation of mouse vomeronasal neurones. Eur J Neurosci. 1998 Jan;10(1):392-6
  • Latest
    J:350968 Pfeffer T, et al., Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet. Antioxidants (Basel). 2023 Jun 14;12(6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory