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Lrrc61 Gene Detail
Summary
  • Symbol
    Lrrc61
  • Name
    leucine rich repeat containing 61
  • Feature Type
    protein coding gene
  • IDs
    MGI:2652848
    NCBI Gene: 243371
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48531732-48547656 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 23.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    597 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2652848
protein coding gene Chr6:48531730-48547656 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030696
protein coding gene Chr6:47502624-47520808 (+)
A/J MGP_AJ_G0030667
protein coding gene Chr6:45343743-45360366 (+)
AKR/J MGP_AKRJ_G0030592
protein coding gene Chr6:46936713-46954520 (+)
BALB/cJ MGP_BALBcJ_G0030677
protein coding gene Chr6:45675003-45690974 (+)
C3H/HeJ MGP_C3HHeJ_G0030390
protein coding gene Chr6:46941935-46959151 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031132
protein coding gene Chr6:48623076-48639211 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028339
protein coding gene Chr6:42976136-42990539 (+)
CAST/EiJ MGP_CASTEiJ_G0029794
protein coding gene Chr6:46662035-46682457 (+)
CBA/J MGP_CBAJ_G0030365
protein coding gene Chr6:50630942-50653550 (+)
DBA/2J MGP_DBA2J_G0030514
protein coding gene Chr6:45261038-45276752 (+)
FVB/NJ MGP_FVBNJ_G0030466
protein coding gene Chr6:44890889-44906710 (+)
LP/J MGP_LPJ_G0030599
protein coding gene Chr6:47482930-47499750 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030500
protein coding gene Chr6:53451201-53467295 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031161
protein coding gene Chr6:46806805-46824731 (+)
PWK/PhJ MGP_PWKPhJ_G0029506
protein coding gene Chr6:44794436-44810514 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029342
protein coding gene Chr6:46153018-46173875 (+)
WSB/EiJ MGP_WSBEiJ_G0029871
protein coding gene Chr6:46805737-46821594 (+)



Homology
more
  • Human Ortholog
    LRRC61, leucine rich repeat containing 61
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC61, leucine rich repeat containing 61
  • Synonyms
    HSPC295
  • Links
    NCBI Gene ID: 65999
    neXtProt AC: NX_Q9BV99
    UniProt: Q9BV99

  • Chr Location
    7q36.1; chr7:150309499-150338156 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 243371 NCBI Gene Model | MGI Sequence Detail 15925 C57BL/6J ±  kb
transcript NM_001411648 RefSeq | MGI Sequence Detail 2841 C57BL/6  
polypeptide Q8R2R5 UniProt | EBI | MGI Sequence Detail 259 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
References
more
  • Summaries
    All 21
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory