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Mrpl21 Gene Detail
Summary
  • Symbol
    Mrpl21
  • Name
    mitochondrial ribosomal protein L21
  • Synonyms
    MGC:41352
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660674
    NCBI Gene: 353242
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3332997-3342837 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 3.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2660674
 protein coding gene Chr19:3332901-3342837 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024622
 protein coding gene Chr19:26689-38604 (+)
A/J MGP_AJ_G0024589
 protein coding gene Chr19:47927-58107 (+)
AKR/J MGP_AKRJ_G0024560
 protein coding gene Chr19:35029-45025 (+)
BALB/cJ MGP_BALBcJ_G0024587
 protein coding gene Chr19:35844-45788 (+)
C3H/HeJ MGP_C3HHeJ_G0024356
 protein coding gene Chr19:33435-43365 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025035
 protein coding gene Chr19:24986-34921 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022464
 protein coding gene Chr19:31545-41492 (+)
CAST/EiJ MGP_CASTEiJ_G0023828
 protein coding gene Chr19:30649-40601 (+)
CBA/J MGP_CBAJ_G0024326
 protein coding gene Chr19:38639-48603 (+)
DBA/2J MGP_DBA2J_G0024455
 protein coding gene Chr19:33529-43464 (+)
FVB/NJ MGP_FVBNJ_G0024422
 protein coding gene Chr19:30674-44110 (+)
LP/J MGP_LPJ_G0024541
 protein coding gene Chr19:36107-46044 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024452
 protein coding gene Chr19:39383-49318 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025083
 protein coding gene Chr19:23861-33801 (+)
PWK/PhJ MGP_PWKPhJ_G0023574
 protein coding gene Chr19:37264-47273 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023380
 protein coding gene Chr19:24584-32499 (+)
WSB/EiJ MGP_WSBEiJ_G0023891
 protein coding gene Chr19:27109-37051 (+)



Homology
more
  • Human Ortholog
    MRPL21, mitochondrial ribosomal protein L21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL21, mitochondrial ribosomal protein L21
  • Synonyms
    bL21m, L21mt, MRP-L21
  • Links
    NCBI Gene ID: 219927
    neXtProt AC: NX_Q7Z2W9
    UniProt: Q7Z2W9

  • Chr Location
    11q13.3; chr11:68891276-68903835 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    19
  • cDNA Data
    83
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 353242 NCBI Gene Model | MGI Sequence Detail 9841 C57BL/6J ±  kb
transcript NM_172252 RefSeq | MGI Sequence Detail 997 C57BL/6  
polypeptide Q9D1N9 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010584 large ribosomal subunit protein bL21m
    (term hierarchy)
  • InterPro Domains
    IPR001787 Large ribosomal subunit protein bL21
    IPR028909 Large ribosomal subunit protein bL21-like
    IPR036164 Large ribosomal subunit protein bL21-like superfamily
Molecular
Reagents
less
  • All nucleic 86
    cDNA 83
    Primer pair 2
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory