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Srsf12 Gene Detail
Summary
  • Symbol
    Srsf12
  • Name
    serine and arginine-rich splicing factor 12
  • Synonyms
    Sfrs13b, Srrp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2661424
    NCBI Gene: 272009
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:33208991-33233340 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 14.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    800 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2661424
 protein coding gene Chr4:33208991-33233344 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028121
 protein coding gene Chr4:30718161-30743202 (+)
A/J MGP_AJ_G0028079
 protein coding gene Chr4:29618624-29643577 (+)
AKR/J MGP_AKRJ_G0028042
 protein coding gene Chr4:30394343-30421978 (+)
BALB/cJ MGP_BALBcJ_G0028090
 protein coding gene Chr4:29877440-29901655 (+)
C3H/HeJ MGP_C3HHeJ_G0027819
 protein coding gene Chr4:30687840-30714193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028532
 protein coding gene Chr4:31923596-31947873 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025873
 protein coding gene Chr4:27788754-27811798 (+)
CAST/EiJ MGP_CASTEiJ_G0027274
 protein coding gene Chr4:30467289-30491457 (+)
CBA/J MGP_CBAJ_G0027791
 protein coding gene Chr4:32952987-32984457 (+)
DBA/2J MGP_DBA2J_G0027935
 protein coding gene Chr4:29618154-29642543 (+)
FVB/NJ MGP_FVBNJ_G0027901
 protein coding gene Chr4:29049574-29074108 (+)
LP/J MGP_LPJ_G0028043
 protein coding gene Chr4:30804496-30828603 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027934
 protein coding gene Chr4:35529365-35555527 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028591
 protein coding gene Chr4:30398306-30423193 (+)
PWK/PhJ MGP_PWKPhJ_G0026993
 protein coding gene Chr4:29621638-29646618 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026822
 protein coding gene Chr4:30284435-30309486 (+)
WSB/EiJ MGP_WSBEiJ_G0027350
 protein coding gene Chr4:30402260-30428147 (+)



Homology
more
  • Human Ortholog
    SRSF12, serine and arginine rich splicing factor 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRSF12, serine and arginine rich splicing factor 12
  • Synonyms
    SFRS13B, SFRS19, SRrp35
  • Links
    NCBI Gene ID: 135295
    neXtProt AC: NX_Q8WXF0
    UniProt: Q8WXF0

  • Chr Location
    6q15; chr6:89095959-89118071 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054679 Ensembl Gene Model | MGI Sequence Detail 24350 C57BL/6J ±  kb
transcript ENSMUST00000067864 Ensembl | MGI Sequence Detail 2939 Not Applicable  
polypeptide ENSMUSP00000067939 Ensembl | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:163097 Thoren LA, et al., UPF2 is a critical regulator of liver development, function and regeneration. PLoS One. 2010;5(7):e11650
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory