Crsl Gene Detail

Summary

• Symbol
  Crsl
• Name
  carousel
• Synonyms
  WBE4

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:2662567
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  19 phenotypes from 1 allele in 2 genetic backgrounds
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice heterozygous for an ENU-induced mutation exhibit partial postnatal lethality, hyperactivity, head-bobbing, circling, variable defects of the stapes and lateral semicircular canal, increased cochlear hair cell number, dry eyes, and vulval and clitoral defects.

References

• Summaries
  All 2

  Phenotypes 2
• Earliest
  J:99481 Hawker K, et al., Two new mouse mutants with vestibular defects that map to the highly mutable locus on chromosome 4. Int J Audiol. 2005 Mar;44(3):171-7
• Latest
  J:104123 Bosman EA, et al., Multiple mutations in mouse Chd7 provide models for CHARGE syndrome. Hum Mol Genet. 2005 Nov 15;14(22):3463-76