About   Help   FAQ
Pkd1l3 Gene Detail
Summary
  • Symbol
    Pkd1l3
  • Name
    polycystic kidney disease 1 like 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2664670
    NCBI Gene: 244646
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:110340828-110399305 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 57.14 cM, cytoband A
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1794 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664670
 protein coding gene Chr8:110340828-110401018 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034110
 protein coding gene Chr8:112211281-112283816 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0034016
 protein coding gene Chr8:110825033-110887057 (+)
BALB/cJ MGP_BALBcJ_G0034083
 protein coding gene Chr8:107879858-107938415 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0034603
 protein coding gene Chr8:116185915-116248509 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031545
 protein coding gene Chr8:100706203-100763078 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0033768
 protein coding gene Chr8:120074854-120146332 (+)
DBA/2J MGP_DBA2J_G0033923
 protein coding gene Chr8:106993770-107057796 (+)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0033913
 protein coding gene Chr8:123113128-123174816 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034622
 protein coding gene Chr8:110780100-110848072 (+)
PWK/PhJ MGP_PWKPhJ_G0032824
 protein coding gene Chr8:106560284-106625762 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032663
 protein coding gene Chr8:109470597-109534799 (+)
WSB/EiJ MGP_WSBEiJ_G0033237
 protein coding gene Chr8:111472089-111533680 (+)



Homology
more
  • Human Ortholog
    PKD1L3, polycystin 1 like 3, transient receptor potential channel interacting
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PKD1L3, polycystin 1 like 3, transient receptor potential channel interacting
  • Links
    NCBI Gene ID: 342372
    neXtProt AC: NX_Q7Z443
    UniProt: Q7Z443

  • Chr Location
    16q22.2; chr16:71929538-72000402 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    15 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and grossly normal and exhibit normal taste responsiveness in various behavioral and electrophysiological tests of taste function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    27
  • cDNA Data
    7
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 244646 NCBI Gene Model | MGI Sequence Detail 58478 C57BL/6J ±  kb
transcript NM_001039700 RefSeq | MGI Sequence Detail 6970 C57BL/6  
polypeptide Q2EG98 UniProt | EBI | MGI Sequence Detail 2201 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 7
    Primer pair 3
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 15
  • Earliest
    J:83807 Li A, et al., Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes. (Erratum: Genomics 2003;82:498-500). Genomics. 2003 Jun;81(6):596-608
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory