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Eras Gene Detail
Summary
  • Symbol
    Eras
  • Name
    ES cell-expressed Ras
  • Synonyms
    ecat5, Ha-Ras2, HRAS2, HRasp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2665023
    NCBI Gene: 353283
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:7790515-7794846 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 3.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2665023
 protein coding gene ChrX:7790515-7794846 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035534
 protein coding gene ChrX:2550741-2555073 (-)
A/J MGP_AJ_G0035511
 protein coding gene ChrX:2508526-2512857 (-)
AKR/J MGP_AKRJ_G0035444
 protein coding gene ChrX:2629079-2633417 (-)
BALB/cJ MGP_BALBcJ_G0035508
 protein coding gene ChrX:2536692-2541010 (-)
C3H/HeJ MGP_C3HHeJ_G0035216
 protein coding gene ChrX:2599643-2604082 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036032
 protein coding gene ChrX:2638426-2642753 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032907
 protein coding gene ChrX:2070120-2074445 (-)
CAST/EiJ MGP_CASTEiJ_G0034517
 protein coding gene ChrX:2489800-2494103 (-)
CBA/J MGP_CBAJ_G0035186
 protein coding gene ChrX:2763408-2767736 (-)
DBA/2J MGP_DBA2J_G0035343
 protein coding gene ChrX:2531805-2536126 (-)
FVB/NJ MGP_FVBNJ_G0035290
 protein coding gene ChrX:2492707-2497569 (-)
LP/J MGP_LPJ_G0035420
 protein coding gene ChrX:2573996-2578327 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035330
 protein coding gene ChrX:2727144-2731511 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036050
 protein coding gene ChrX:2536815-2541136 (-)
PWK/PhJ MGP_PWKPhJ_G0034217
 protein coding gene ChrX:2462658-2467093 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034056
 protein coding gene ChrX:2510655-2518357 (-)
WSB/EiJ MGP_WSBEiJ_G0034640
 protein coding gene ChrX:2544821-2549160 (-)



Homology
more
  • Human Ortholog
    ERAS, ES cell expressed Ras
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERAS, ES cell expressed Ras
  • Synonyms
    HRAS2, HRASP
  • Links
    NCBI Gene ID: 3266
    neXtProt AC: NX_Q7Z444
    UniProt: Q7Z444

  • Chr Location
    Xp11.23; chrX:48826513-48830138 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    795
  • Tissues
    38
  • cDNA Data
    6
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 353283 NCBI Gene Model | MGI Sequence Detail 4332 C57BL/6J ±  kb
transcript NM_181548 RefSeq | MGI Sequence Detail 1077 Not Specified  
polypeptide Q7TN89 UniProt | EBI | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 6
    Primer pair 3
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:83420 Mitsui K, et al., The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003 May 30;113(5):631-42
  • Latest
    J:310310 Gordeeva O, et al., Expression dynamics of Mage family genes during self-renewal and differentiation of mouse pluripotent stem and teratocarcinoma cells. Oncotarget. 2019 May 14;10(35):3248-3266
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory