About   Help   FAQ
Nanos1 Gene Detail
Summary
  • Symbol
    Nanos1
  • Name
    nanos C2HC-type zinc finger 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2669254
    NCBI Gene: 332397
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:60744425-60748352 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 56.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2669254
 protein coding gene Chr19:60744425-60748352 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025294
 protein coding gene Chr19:61356601-61360535 (+)
A/J MGP_AJ_G0025270
 protein coding gene Chr19:58359022-58363012 (+)
AKR/J MGP_AKRJ_G0025239
 protein coding gene Chr19:60178079-60182009 (+)
BALB/cJ MGP_BALBcJ_G0025265
 protein coding gene Chr19:58441120-58445050 (+)
C3H/HeJ MGP_C3HHeJ_G0025025
 protein coding gene Chr19:60422201-60426131 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025708
 protein coding gene Chr19:62811912-62815838 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023120
 protein coding gene Chr19:57192897-57196826 (+)
CAST/EiJ MGP_CASTEiJ_G0024490
 protein coding gene Chr19:60527031-60530985 (+)
CBA/J MGP_CBAJ_G0025005
 protein coding gene Chr19:65873335-65877265 (+)
DBA/2J MGP_DBA2J_G0025137
 protein coding gene Chr19:58141126-58145056 (+)
FVB/NJ MGP_FVBNJ_G0025098
 protein coding gene Chr19:57812432-57816373 (+)
LP/J MGP_LPJ_G0025223
 protein coding gene Chr19:61194503-61198434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025131
 protein coding gene Chr19:65070407-65074355 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025766
 protein coding gene Chr19:60424950-60428890 (+)
PWK/PhJ MGP_PWKPhJ_G0024238
 protein coding gene Chr19:58087268-58091256 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024041
 protein coding gene Chr19:59071344-59075265 (+)
WSB/EiJ MGP_WSBEiJ_G0024560
 protein coding gene Chr19:60529838-60533779 (+)



Homology
more
  • Human Ortholog
    NANOS1, nanos C2HC-type zinc finger 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NANOS1, nanos C2HC-type zinc finger 1
  • Synonyms
    EC_Rep1a, NOS-1, NOS1, SPGF12, ZC2HC12A
  • Links
    NCBI Gene ID: 340719
    neXtProt AC: NX_Q8WY41
    UniProt: Q8WY41

  • Chr Location
    10q26.11; chr10:119029714-119033730 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NANOS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Mice homozygous for disruptions in this gene display no phenotypic alterations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    841
  • Tissues
    84
  • cDNA Data
    21
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 332397 NCBI Gene Model | MGI Sequence Detail 3928 C57BL/6J ±  kb
transcript NM_178421 RefSeq | MGI Sequence Detail 3945 C57BL/6  
polypeptide Q80WY3 UniProt | EBI | MGI Sequence Detail 267 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 21
    Primer pair 3
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 2
  • Earliest
    J:83558 Jaruzelska J, et al., Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. Dev Genes Evol. 2003 Apr;213(3):120-6
  • Latest
    J:227840 Amadei G, et al., A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis. J Neurosci. 2015 Nov 25;35(47):15666-81
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory