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Zfp598 Gene Detail
Summary
  • Symbol
    Zfp598
  • Name
    zinc finger protein 598
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670965
    NCBI Gene: 213753
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24888661-24900990 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    339 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670965
 protein coding gene Chr17:24888661-24900997 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023312
 protein coding gene Chr17:23675317-23690334 (+)
A/J MGP_AJ_G0023272
 protein coding gene Chr17:23032703-23045785 (+)
AKR/J MGP_AKRJ_G0023239
 protein coding gene Chr17:23110758-23123907 (+)
BALB/cJ MGP_BALBcJ_G0023277
 protein coding gene Chr17:23216959-23229296 (+)
C3H/HeJ MGP_C3HHeJ_G0023037
 protein coding gene Chr17:23470005-23482661 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023721
 protein coding gene Chr17:24725910-24738233 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0023013
 protein coding gene Chr17:25568735-25582440 (+)
DBA/2J MGP_DBA2J_G0023142
 protein coding gene Chr17:22623082-22635480 (+)
FVB/NJ MGP_FVBNJ_G0023112
 protein coding gene Chr17:22341318-22355477 (+)
LP/J MGP_LPJ_G0023219
 protein coding gene Chr17:23985393-23997678 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023131
 protein coding gene Chr17:25274269-25288473 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023758
 protein coding gene Chr17:23392475-23406646 (+)
PWK/PhJ MGP_PWKPhJ_G0022288
 protein coding gene Chr17:21368456-21380840 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022106
 protein coding gene Chr17:21432875-21446171 (+)
WSB/EiJ MGP_WSBEiJ_G0022602
 protein coding gene Chr17:23458409-23472872 (+)



Homology
more
  • Human Ortholog
    ZNF598, zinc finger protein 598, E3 ubiquitin ligase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF598, zinc finger protein 598, E3 ubiquitin ligase
  • Synonyms
    HEL2
  • Links
    NCBI Gene ID: 90850
    neXtProt AC: NX_Q86UK7
    UniProt: Q86UK7

  • Chr Location
    16p13.3; chr16:1997654-2009821 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    9
  • cDNA Data
    82
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041130 Ensembl Gene Model | MGI Sequence Detail 12330 C57BL/6J ±  kb
transcript ENSMUST00000234956 Ensembl | MGI Sequence Detail 3352 Not Applicable  
polypeptide ENSMUSP00000157172 Ensembl | MGI Sequence Detail 908 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 83
    cDNA 82
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory