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Kics2 Gene Detail
Summary
  • Symbol
    Kics2
  • Name
    KICSTOR subunit 2
  • Synonyms
    BC048403
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670984
    NCBI Gene: 270802
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:121575835-121588770 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 69.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    481 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670984
 protein coding gene Chr10:121575835-121588783 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017786
 protein coding gene Chr10:125032475-125048014 (+)
A/J MGP_AJ_G0017761
 protein coding gene Chr10:120033259-120046994 (+)
AKR/J MGP_AKRJ_G0017724
 protein coding gene Chr10:123622014-123634962 (+)
BALB/cJ MGP_BALBcJ_G0017725
 protein coding gene Chr10:120461030-120473788 (+)
C3H/HeJ MGP_C3HHeJ_G0017549
 protein coding gene Chr10:123827496-123840967 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018180
 protein coding gene Chr10:129282809-129295737 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015860
 protein coding gene Chr10:114354819-114368436 (+)
CAST/EiJ MGP_CASTEiJ_G0017109
 protein coding gene Chr10:124218412-124232554 (+)
CBA/J MGP_CBAJ_G0017518
 protein coding gene Chr10:134544209-134557127 (+)
DBA/2J MGP_DBA2J_G0017624
 protein coding gene Chr10:119170980-119184562 (+)
FVB/NJ MGP_FVBNJ_G0017619
 protein coding gene Chr10:118161639-118175089 (+)
LP/J MGP_LPJ_G0017698
 protein coding gene Chr10:125557341-125570315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017647
 protein coding gene Chr10:137072865-137087080 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018220
 protein coding gene Chr10:123674148-123687272 (+)
PWK/PhJ MGP_PWKPhJ_G0016894
 protein coding gene Chr10:119293696-119307390 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016685
 protein coding gene Chr10:122546173-122559054 (+)
WSB/EiJ MGP_WSBEiJ_G0017170
 protein coding gene Chr10:123863088-123876798 (+)



Homology
more
  • Human Ortholog
    KICS2, KICSTOR subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KICS2, KICSTOR subunit 2
  • Synonyms
    C12orf66
  • Links
    NCBI Gene ID: 144577
    neXtProt AC: NX_Q96MD2
    UniProt: Q96MD2

  • Chr Location
    12q14.2; chr12:64186316-64222296 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 270802 NCBI Gene Model | MGI Sequence Detail 12936 C57BL/6J ±  kb
    transcript NM_173022 RefSeq | MGI Sequence Detail 3130 C57BL/6  
    polypeptide Q6P1I3 UniProt | EBI | MGI Sequence Detail 445 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 2
      cDNA 15

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:6715943
    References
    more
    • Summaries
      All 30
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory