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Lgsn Gene Detail
Summary
  • Symbol
    Lgsn
  • Name
    lengsin, lens protein with glutamine synthetase domain
  • Synonyms
    Gluld1, lengsin, Lgs
  • Feature Type
    protein coding gene
  • IDs
    MGI:2672844
    NCBI Gene: 266744
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:31215482-31243806 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 11.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    863 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2672844
 protein coding gene Chr1:31215362-31243806 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015898
 protein coding gene Chr1:29409813-29446341 (+)
A/J MGP_AJ_G0015881
 protein coding gene Chr1:28700772-28730828 (+)
AKR/J MGP_AKRJ_G0015836
 protein coding gene Chr1:29038940-29068673 (+)
BALB/cJ MGP_BALBcJ_G0015835
 protein coding gene Chr1:28430861-28461655 (+)
C3H/HeJ MGP_C3HHeJ_G0015669
 protein coding gene Chr1:29208507-29242415 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016289
 protein coding gene Chr1:30746365-30781629 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014008
 protein coding gene Chr1:26205956-26234724 (+)
CAST/EiJ MGP_CASTEiJ_G0015248
 protein coding gene Chr1:29104468-29137940 (+)
CBA/J MGP_CBAJ_G0015641
 protein coding gene Chr1:31589330-31627904 (+)
DBA/2J MGP_DBA2J_G0015741
 protein coding gene Chr1:28144691-28174976 (+)
FVB/NJ MGP_FVBNJ_G0015744
 protein coding gene Chr1:27704340-27738060 (+)
LP/J MGP_LPJ_G0015812
 protein coding gene Chr1:29684286-29717185 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015764
 protein coding gene Chr1:33664478-33697300 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016336
 protein coding gene Chr1:28999593-29027967 (+)
PWK/PhJ MGP_PWKPhJ_G0015033
 protein coding gene Chr1:27827626-27857259 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014812
 protein coding gene Chr1:29045653-29083600 (+)
WSB/EiJ MGP_WSBEiJ_G0015312
 protein coding gene Chr1:28960648-28996144 (+)



Homology
more
  • Human Ortholog
    LGSN, lengsin, lens protein with glutamine synthetase domain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LGSN, lengsin, lens protein with glutamine synthetase domain
  • Synonyms
    GLULD1, LGS
  • Links
    NCBI Gene ID: 51557
    neXtProt AC: NX_Q5TDP6
    UniProt: Q5TDP6

  • Chr Location
    6q12; chr6:63275951-63573607 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050217 Ensembl Gene Model | MGI Sequence Detail 28325 C57BL/6J ±  kb
transcript ENSMUST00000062560 Ensembl | MGI Sequence Detail 1937 Not Applicable  
polypeptide ENSMUSP00000059871 Ensembl | MGI Sequence Detail 563 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory