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Mir127 Gene Detail
Summary
  • Symbol
    Mir127
  • Name
    microRNA 127
  • Synonyms
    Mirn127, mmu-mir-127
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676812
    NCBI Gene: 387146
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr12:109559280-109559349 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676812
 miRNA gene Chr12:109559280-109559349 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007969
 miRNA gene Chr12:111823002-111823071 (+)
A/J MGP_AJ_G0007963
 miRNA gene Chr12:107515915-107515984 (+)
AKR/J MGP_AKRJ_G0007940
 miRNA gene Chr12:110653192-110653261 (+)
BALB/cJ MGP_BALBcJ_G0007942
 miRNA gene Chr12:107989328-107989397 (+)
C3H/HeJ MGP_C3HHeJ_G0007888
 miRNA gene Chr12:111095038-111095107 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008123
 miRNA gene Chr12:115240918-115240987 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007250
 miRNA gene Chr12:104042222-104042291 (+)
CAST/EiJ MGP_CASTEiJ_G0007776
 miRNA gene Chr12:106045773-106045842 (+)
CBA/J MGP_CBAJ_G0007858
 miRNA gene Chr12:119780374-119780443 (+)
DBA/2J MGP_DBA2J_G0007893
 miRNA gene Chr12:107070939-107071008 (+)
FVB/NJ MGP_FVBNJ_G0007912
 miRNA gene Chr12:105861608-105861677 (+)
LP/J MGP_LPJ_G0007974
 miRNA gene Chr12:111650546-111650615 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007883
 miRNA gene Chr12:122936724-122936793 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008118
 miRNA gene Chr12:110134693-110134762 (+)
PWK/PhJ MGP_PWKPhJ_G0007699
 miRNA gene Chr12:101679248-101679317 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007595
 miRNA gene Chr12:104304618-104304687 (+)
WSB/EiJ MGP_WSBEiJ_G0007845
 miRNA gene Chr12:111047509-111047578 (+)



Homology
more
  • Human Ortholog
    MIR127, microRNA 127
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR127, microRNA 127
  • Synonyms
    mir-127, MIRN127, miRNA127
  • Links
    NCBI Gene ID: 406914

  • Chr Location
    chr14:100882979-100883075 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MIR127 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from multigenic genotypes
    3 phenotype references
Mice heterozygous for a knock-out allele exhibit increased placenta weight and placental transport when the allele is inherited maternally and reduced placenta weight, decreased placental transport and some neonatal lethality when this allele is inherited paternally.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    27
  • Literature Summary
    20
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387146 NCBI Gene Model | MGI Sequence Detail 70 C57BL/6J ±  kb
transcript NR_029542 RefSeq | MGI Sequence Detail 70 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 11
    Primer pair 7
    Other 4
Other Database
Links
less
miRBase MI0000154
References
more
  • Summaries
    All 38
    Developmental Gene Expression 20
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:353308 Teng X, et al., LncRNAs in the Dlk1-Dio3 Domain Are Essential for Mid-Embryonic Heart Development. Int J Mol Sci. 2024 Jul 26;25(15)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory