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Mir184 Gene Detail
Summary
  • Symbol
    Mir184
  • Name
    microRNA 184
  • Synonyms
    Mirn184, mmu-mir-184
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676848
    NCBI Gene: 387179
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:89684313-89684381 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 47.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676848
miRNA gene Chr9:89684313-89684381 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009224
miRNA gene Chr9:90729700-90729768 (-)
A/J MGP_AJ_G0009205
miRNA gene Chr9:87593175-87593243 (-)
AKR/J MGP_AKRJ_G0009194
miRNA gene Chr9:89657315-89657383 (-)
BALB/cJ MGP_BALBcJ_G0009189
miRNA gene Chr9:87239831-87239899 (-)
C3H/HeJ MGP_C3HHeJ_G0009130
miRNA gene Chr9:90091949-90092017 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009431
miRNA gene Chr9:93257208-93257276 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008286
miRNA gene Chr9:85776041-85776109 (-)
CAST/EiJ MGP_CASTEiJ_G0008960
miRNA gene Chr9:89879364-89879432 (-)
CBA/J MGP_CBAJ_G0009095
miRNA gene Chr9:96484155-96484223 (-)
DBA/2J MGP_DBA2J_G0009125
miRNA gene Chr9:87141254-87141322 (-)
FVB/NJ MGP_FVBNJ_G0009143
miRNA gene Chr9:86163500-86163568 (-)
LP/J MGP_LPJ_G0009222
miRNA gene Chr9:90955102-90955170 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009109
miRNA gene Chr9:98113202-98113270 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009401
miRNA gene Chr9:89875941-89876009 (-)
PWK/PhJ MGP_PWKPhJ_G0008885
miRNA gene Chr9:87302244-87302312 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008724
miRNA gene Chr9:89939582-89939650 (-)
WSB/EiJ MGP_WSBEiJ_G0009054
miRNA gene Chr9:89756172-89756240 (-)



Homology
more
  • Human Ortholog
    MIR184, microRNA 184
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR184, microRNA 184
  • Synonyms
    EDICT, miR-184, MIRN184
  • Links
    NCBI Gene ID: 406960

  • Chr Location
    chr15:79209788-79209871 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 3 alleles in 1 genetic background
    6 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased fasted circulating glucose, increased fasted circulating insulin and improved glucose tolerance with increased beta-cell mass and beta cell proliferation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387179 NCBI Gene Model | MGI Sequence Detail 69 C57BL/6J ±  kb
    transcript NR_029570 RefSeq | MGI Sequence Detail 69 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 7
      Primer pair 4
      Other 3
    Other Database
    Links
    less
    miRBase MI0000226
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 12
      Gene Ontology 4
      Phenotypes 7
    • Earliest
      J:84908 Lagos-Quintana M, et al., New microRNAs from mouse and human. RNA. 2003 Feb;9(2):175-9
    • Latest
      J:345791 Turovsky L, et al., miR-184 represses beta-catenin and behaves as a skin tumor suppressor. Cell Death Dis. 2024 Feb 26;15(2):174

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/05/2024
    MGI 6.24
    The Jackson Laboratory