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Kyat3 Gene Detail
Summary
  • Symbol
    Kyat3
  • Name
    kynurenine aminotransferase 3
  • Synonyms
    Ccbl2, Kat3, KATIII
  • Feature Type
    protein coding gene
  • IDs
    MGI:2677849
    NCBI Gene: 229905
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:142406780-142450672 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 66.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1621 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2677849
 protein coding gene Chr3:142406780-142452631 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027946
 protein coding gene Chr3:145910251-145959320 (+)
A/J MGP_AJ_G0027903
 protein coding gene Chr3:140744523-140790344 (+)
AKR/J MGP_AKRJ_G0027869
 protein coding gene Chr3:144496021-144544311 (+)
BALB/cJ MGP_BALBcJ_G0027915
 protein coding gene Chr3:140554702-140601124 (+)
C3H/HeJ MGP_C3HHeJ_G0027645
 protein coding gene Chr3:144808214-144859868 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028359
 protein coding gene Chr3:150977499-151026127 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025697
 protein coding gene Chr3:135958909-136003703 (+)
CAST/EiJ MGP_CASTEiJ_G0027101
 protein coding gene Chr3:144789281-144839036 (+)
CBA/J MGP_CBAJ_G0027622
 protein coding gene Chr3:156267098-156313137 (+)
DBA/2J MGP_DBA2J_G0027761
 protein coding gene Chr3:139906667-139953492 (+)
FVB/NJ MGP_FVBNJ_G0027728
 protein coding gene Chr3:137331523-137378862 (+)
LP/J MGP_LPJ_G0027871
 protein coding gene Chr3:147341314-147388527 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027760
 protein coding gene Chr3:164543762-164593653 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028417
 protein coding gene Chr3:144118790-144164473 (+)
PWK/PhJ MGP_PWKPhJ_G0026825
 protein coding gene Chr3:139722507-139770100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026652
 protein coding gene Chr3:142261442-142314021 (+)
WSB/EiJ MGP_WSBEiJ_G0027180
 protein coding gene Chr3:144990618-145038077 (+)



Homology
more
  • Human Ortholog
    KYAT3, kynurenine aminotransferase 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KYAT3, kynurenine aminotransferase 3
  • Synonyms
    CCBL2, KAT3, KATIII
  • Links
    NCBI Gene ID: 56267
    neXtProt AC: NX_Q6YP21
    UniProt: Q6YP21

  • Chr Location
    1p22.2; chr1:88921044-88992960 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    46
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229905 NCBI Gene Model | MGI Sequence Detail 43893 C57BL/6J ±  kb
transcript NM_173763 RefSeq | MGI Sequence Detail 2279 C57BL/6  
polypeptide Q71RI9 UniProt | EBI | MGI Sequence Detail 455 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 47
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:56834 Yu P, et al., Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease. Mamm Genome. 1999 Sep;10(9):845-52
  • Latest
    J:293419 Lipinski M, et al., KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain. Nat Commun. 2020 May 22;11(1):2588
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory