Slc38a7 MGI Mouse Gene Detail - MGI:2679005 - solute carrier family 38, member 7

Symbol

Slc38a7
Name

solute carrier family 38, member 7
Synonyms

MGC:25764

Feature Type

protein coding gene
IDs

MGI:2679005
NCBI Gene: 234595
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr8:96562548-96580167 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 47.67 cM
Mapping Data

1 experiment

SNPs within 2kb

664 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2679005	protein coding gene	Chr8:96562548-96580205 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0033994	protein coding gene	Chr8:97351428-97369846 (-)
A/J	MGP_AJ_G0033977	protein coding gene	Chr8:93513711-93531233 (-)
AKR/J	MGP_AKRJ_G0033903	protein coding gene	Chr8:96098700-96116357 (-)
BALB/cJ	MGP_BALBcJ_G0033969	protein coding gene	Chr8:93608833-93626724 (-)
C3H/HeJ	MGP_C3HHeJ_G0033679	protein coding gene	Chr8:96806270-96826036 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034490	protein coding gene	Chr8:100922326-100940662 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031431	protein coding gene	Chr8:87315565-87333700 (-)
CAST/EiJ	MGP_CASTEiJ_G0033011	protein coding gene	Chr8:96392120-96413137 (-)
CBA/J	MGP_CBAJ_G0033655	protein coding gene	Chr8:104221888-104243085 (-)
DBA/2J	MGP_DBA2J_G0033809	protein coding gene	Chr8:93013693-93031336 (-)
FVB/NJ	MGP_FVBNJ_G0033756	protein coding gene	Chr8:91971826-91989021 (-)
LP/J	MGP_LPJ_G0033901	protein coding gene	Chr8:97481705-97499127 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033798	protein coding gene	Chr8:106424854-106443294 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034508	protein coding gene	Chr8:96265906-96284210 (-)
PWK/PhJ	MGP_PWKPhJ_G0032713	protein coding gene	Chr8:92379617-92397637 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0032550	protein coding gene	Chr8:95094378-95113202 (-)
WSB/EiJ	MGP_WSBEiJ_G0033123	protein coding gene	Chr8:96775644-96795014 (-)

Human Ortholog

SLC38A7, solute carrier family 38 member 7

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC38A7, solute carrier family 38 member 7
Synonyms

SNAT7
Links

HGNC:25582

NCBI Gene ID: 55238

neXtProt AC: NX_Q9NVC3

UniProt: Q9NVC3
Chr Location

16q21; chr16:58665109-58684770 (-) GRCh38

MGI Vertebrate Homology

Slc38a7 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC38A7
Gene Tree

Slc38a7

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Phenotype Summary

12 phenotypes from 1 allele in 1 genetic background
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

24
Endonuclease-mediated

2
Gene trapped

19
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

33 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

17
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

983
Tissues

113
cDNA Data

45
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN slc38a7

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All Sequences

69
RefSeq

16
UniProt

2
CCDS

CCDS22567.1

Ensembl

ENSMUSG00000036534 (Evidence)
NCBI Gene

234595

			Length	Strain/Species	Flank
genomic	ENSMUSG00000036534	Ensembl Gene Model \| MGI Sequence Detail	17620	C57BL/6J	± kb
transcript	ENSMUST00000040481	Ensembl \| MGI Sequence Detail	3333	Not Applicable
polypeptide	ENSMUSP00000037023	Ensembl \| MGI Sequence Detail	463	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000029738 sodium-coupled neutral amino acid transporter 7

(term hierarchy)
InterPro Domains

IPR013057 Amino acid transporter, transmembrane domain

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All nucleic 45

cDNA 45

Microarray probesets 3

Summaries

All 40

Developmental Gene Expression 2

Gene Ontology 5

Phenotypes 15
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slc38a7:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr82566	Chr8:96580129-96580158 (-)	23 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24