Bahcc1 MGI Mouse Gene Detail - MGI:2679272 - BAH domain and coiled-coil containing 1

Symbol

Bahcc1
Name

BAH domain and coiled-coil containing 1
Synonyms

MGC:79150

Feature Type

protein coding gene
IDs

MGI:2679272
NCBI Gene: 268515
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr11:120123773-120183108 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 83.96 cM
Mapping Data

1 experiment

SNPs within 2kb

1131 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2679272	protein coding gene	Chr11:120123696-120183123 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019493	protein coding gene	Chr11:124682001-124745113 (+)
A/J	MGP_AJ_G0019461	protein coding gene	Chr11:119137960-119201588 (+)
AKR/J	MGP_AKRJ_G0019431	protein coding gene	Chr11:122718390-122778787 (+)
BALB/cJ	MGP_BALBcJ_G0019436	protein coding gene	Chr11:119494867-119555597 (+)
C3H/HeJ	MGP_C3HHeJ_G0019242	protein coding gene	Chr11:123053286-123115695 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019885	protein coding gene	Chr11:128458481-128518815 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017510	protein coding gene	Chr11:116142633-116203472 (+)
CAST/EiJ	MGP_CASTEiJ_G0018796	protein coding gene	Chr11:124529525-124594677 (+)
CBA/J	MGP_CBAJ_G0019213	protein coding gene	Chr11:133480546-133547907 (+)
DBA/2J	MGP_DBA2J_G0019325	protein coding gene	Chr11:118508804-118568517 (+)
FVB/NJ	MGP_FVBNJ_G0019317	protein coding gene	Chr11:118201087-118262536 (+)
LP/J	MGP_LPJ_G0019397	protein coding gene	Chr11:124985862-125050733 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019350	protein coding gene	Chr11:132325754-132393881 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019924	protein coding gene	Chr11:123405681-123464371 (+)
PWK/PhJ	MGP_PWKPhJ_G0018562	protein coding gene	Chr11:119934304-119995025 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018354	protein coding gene	Chr11:123172896-123236190 (+)
WSB/EiJ	MGP_WSBEiJ_G0018848	protein coding gene	Chr11:123402458-123464823 (+)

Human Ortholog

BAHCC1, BAH domain and coiled-coil containing 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

BAHCC1, BAH domain and coiled-coil containing 1
Synonyms

BAHD2
Links

HGNC:29279

NCBI Gene ID: 57597

neXtProt AC: NX_Q9P281

UniProt: Q9P281
Chr Location

17q25.3; chr17:81395457-81466331 (+) GRCh38

MGI Vertebrate Homology

Bahcc1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: BAHCC1
Gene Tree

Bahcc1

less

Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

29
Endonuclease-mediated

1
Gene trapped

24
Targeted

4
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

103 strains or lines available

Homozygous mutation of this gene results in perinatal lethality for the majority of mutants. Those that survive exhibit hind leg motor dysfunction.

less

All GO Annotations

4
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

753
Tissues

34
cDNA Data

66
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

Xenbase bahcc1

ZFIN bahcc1b

less

All Sequences

68
RefSeq

28
UniProt

2
CCDS

CCDS49003.1, CCDS83943.1

Ensembl

ENSMUSG00000039741 (Evidence)
NCBI Gene

268515

			Length	Strain/Species	Flank
genomic	ENSMUSG00000039741	Ensembl Gene Model \| MGI Sequence Detail	59336	C57BL/6J	± kb
transcript	ENSMUST00000122148	Ensembl \| MGI Sequence Detail	10712	Not Applicable
polypeptide	ENSMUSP00000112827	Ensembl \| MGI Sequence Detail	2643	Not Applicable

less

UniProt

2 Sequences
Protein Ontology

PR:000030197 BAH and coiled-coil domain-containing protein 1

(term hierarchy)
PDB

6VIL
InterPro Domains

IPR047411 BAH and coiled-coil domain-containing protein 1, Tudor domain

IPR048924 BAHCC1-like, Tudor domain

IPR052429 BAH domain-containing protein

IPR001025 Bromo adjacent homology (BAH) domain

IPR043151 Bromo adjacent homology (BAH) domain superfamily
GlyGen

Q3UHR0 1 site, 1 O-linked glycan (1 site)

less

All nucleic 66

cDNA 66

Microarray probesets 1

Summaries

All 30

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 9
Earliest

J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
Latest

J:345950 Li J, et al., Transmembrane protein TMEM97 and epigenetic reader BAHCC1 constitute an axis that supports pro-inflammatory cytokine expression. Cell Signal. 2024 Apr;116:111069

TSS for Bahcc1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr106274	Chr11:120123728-120123744 (+)	-37 bp
Tssr106275	Chr11:120123747-120123778 (+)	-10 bp
Tssr106276	Chr11:120123784-120123806 (+)	22 bp
Tssr106277	Chr11:120124754-120124801 (+)	1,005 bp
Tssr106278	Chr11:120127319-120127350 (+)	3,562 bp
Tssr106279	Chr11:120143870-120143889 (+)	20,107 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24