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Tas2r140 Gene Detail
Summary
  • Symbol
    Tas2r140
  • Name
    taste receptor, type 2, member 140
  • Synonyms
    mt2r64, mTRB3, T2R40, Tas2r13, Tas2r40, TRB3, TRB5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681298
    NCBI Gene: 387616
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:133031818-133032756 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 64.03 cM, cytoband F3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681298
protein coding gene Chr6:133031780-133032779 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031398
protein coding gene Chr6:137217786-137218785 (-)
A/J MGP_AJ_G0031374
protein coding gene Chr6:131766622-131767622 (-)
AKR/J MGP_AKRJ_G0031301
protein coding gene Chr6:135671752-135672752 (-)
BALB/cJ MGP_BALBcJ_G0031380
protein coding gene Chr6:131398964-131399964 (-)
C3H/HeJ MGP_C3HHeJ_G0031102
protein coding gene Chr6:135843905-135844905 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031840
protein coding gene Chr6:140904992-140905991 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028972
protein coding gene Chr6:130062609-130063608 (-)
CAST/EiJ MGP_CASTEiJ_G0030472
protein coding gene Chr6:135491468-135492467 (-)
CBA/J MGP_CBAJ_G0031061
protein coding gene Chr6:146172916-146173916 (-)
DBA/2J MGP_DBA2J_G0031219
protein coding gene Chr6:130628114-130629114 (-)
FVB/NJ MGP_FVBNJ_G0031169
protein coding gene Chr6:129626988-129627987 (-)
LP/J MGP_LPJ_G0031303
protein coding gene Chr6:137314543-137315543 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031209
protein coding gene Chr6:150244283-150245282 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031874
protein coding gene Chr6:135617570-135618569 (-)
PWK/PhJ MGP_PWKPhJ_G0030196
protein coding gene Chr6:129048865-129049864 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030020
protein coding gene Chr6:134028890-134029890 (-)
WSB/EiJ MGP_WSBEiJ_G0030562
protein coding gene Chr6:136222788-136223787 (-)



Homology
more
  • Human Ortholog
    TAS2R14, taste 2 receptor member 14
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAS2R14, taste 2 receptor member 14
  • Synonyms
    T2R14, TRB1
  • Links
    NCBI Gene ID: 50840
    neXtProt AC: NX_Q9NYV8
    UniProt: Q9NYV8

  • Chr Location
    12p13.2; chr12:10937408-11171573 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 387616 NCBI Gene Model | MGI Sequence Detail 939 C57BL/6J ±  kb
transcript NM_021562 RefSeq | MGI Sequence Detail 939 Not Specified  
polypeptide Q7TQA4 UniProt | EBI | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
Other
Accession IDs
less
MGI:1890148, MGI:1890259
References
more
  • Summaries
    All 24
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:61439 Matsunami H, et al., A family of candidate taste receptors in human and mouse [see comments]. Nature. 2000 Apr 6;404(6778):601-4
  • Latest
    J:101833 Nelson TM, et al., Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice. BMC Genet. 2005 Jun 6;6(1):32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory