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Tnpo1 Gene Detail
Summary
  • Symbol
    Tnpo1
  • Name
    transportin 1
  • Synonyms
    D13Ertd688e, Kpnb2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681523
    NCBI Gene: 238799
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:98975527-99062851 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 52.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1955 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681523
 protein coding gene Chr13:98975527-99062892 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020871
 protein coding gene Chr13:100595381-100686031 (-)
A/J MGP_AJ_G0020825
 protein coding gene Chr13:96752070-96837676 (-)
AKR/J MGP_AKRJ_G0020799
 protein coding gene Chr13:99703323-99793252 (-)
BALB/cJ MGP_BALBcJ_G0020823
 protein coding gene Chr13:97460994-97547279 (-)
C3H/HeJ MGP_C3HHeJ_G0020614
 protein coding gene Chr13:99452698-99536574 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021257
 protein coding gene Chr13:103599035-103701365 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018826
 protein coding gene Chr13:92483043-92571894 (-)
CAST/EiJ MGP_CASTEiJ_G0020132
 protein coding gene Chr13:98823847-98916908 (-)
CBA/J MGP_CBAJ_G0020574
 protein coding gene Chr13:107740564-107826758 (-)
DBA/2J MGP_DBA2J_G0020699
 protein coding gene Chr13:96522838-96602650 (-)
FVB/NJ MGP_FVBNJ_G0020680
 protein coding gene Chr13:95272080-95354859 (-)
LP/J MGP_LPJ_G0020774
 protein coding gene Chr13:100699539-100783675 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020708
 protein coding gene Chr13:108048541-108143698 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021298
 protein coding gene Chr13:99157108-99243761 (-)
PWK/PhJ MGP_PWKPhJ_G0019885
 protein coding gene Chr13:95327994-95415302 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019708
 protein coding gene Chr13:95449859-95535553 (-)
WSB/EiJ MGP_WSBEiJ_G0020190
 protein coding gene Chr13:99603813-99688813 (-)



Homology
more
  • Human Ortholog
    TNPO1, transportin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TNPO1, transportin 1
  • Synonyms
    IPO2, KPNB2, MIP, MIP1, TRN
  • Links
    NCBI Gene ID: 3842
    neXtProt AC: NX_Q92973
    UniProt: Q92973

  • Chr Location
    5q13.2; chr5:72816312-72916733 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    24
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 238799 NCBI Gene Model | MGI Sequence Detail 87325 C57BL/6J ±  kb
transcript NM_001048267 RefSeq | MGI Sequence Detail 8434 ZRU/MplStud  
polypeptide Q8BFY9 UniProt | EBI | MGI Sequence Detail 898 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 24
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:1277121, MGI:2145358
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory