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Lrrc75a Gene Detail
Summary
  • Symbol
    Lrrc75a
  • Name
    leucine rich repeat containing 75A
  • Synonyms
    BC046404, Fam211a, MGC:59632
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682293
    NCBI Gene: 192976
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:62495710-62539349 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 38.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1284 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682293
 protein coding gene Chr11:62495708-62539411 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018458
 protein coding gene Chr11:62653289-62702664 (-)
A/J MGP_AJ_G0018427
 protein coding gene Chr11:60337702-60386497 (-)
AKR/J MGP_AKRJ_G0018396
 protein coding gene Chr11:62199567-62244432 (-)
BALB/cJ MGP_BALBcJ_G0018398
 protein coding gene Chr11:60620305-60666057 (-)
C3H/HeJ MGP_C3HHeJ_G0018211
 protein coding gene Chr11:62179806-62225552 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018850
 protein coding gene Chr11:64633431-64678205 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016495
 protein coding gene Chr11:57429802-57473657 (-)
CAST/EiJ MGP_CASTEiJ_G0017767
 protein coding gene Chr11:62321626-62369798 (-)
CBA/J MGP_CBAJ_G0018185
 protein coding gene Chr11:67419543-67466219 (-)
DBA/2J MGP_DBA2J_G0018294
 protein coding gene Chr11:59898626-59941529 (-)
FVB/NJ MGP_FVBNJ_G0018284
 protein coding gene Chr11:59566292-59610554 (-)
LP/J MGP_LPJ_G0018366
 protein coding gene Chr11:63207909-63254258 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018308
 protein coding gene Chr11:68408956-68455096 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018891
 protein coding gene Chr11:62354663-62399375 (-)
PWK/PhJ MGP_PWKPhJ_G0017541
 protein coding gene Chr11:60500585-60560752 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017331
 protein coding gene Chr11:62181141-62249553 (-)
WSB/EiJ MGP_WSBEiJ_G0017820
 protein coding gene Chr11:61968735-62015901 (-)



Homology
more
  • Human Ortholog
    LRRC75A, leucine rich repeat containing 75A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC75A, leucine rich repeat containing 75A
  • Synonyms
    C17orf76, FAM211A
  • Links
    NCBI Gene ID: 388341
    neXtProt AC: NX_Q8NAA5
    UniProt: Q8NAA5

  • Chr Location
    17p11.2; chr17:16441577-16492193 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    15
  • Targeted
    2
  • Genomic Mutations
    1 involving Lrrc75a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046417 Ensembl Gene Model | MGI Sequence Detail 43640 C57BL/6J ±  kb
transcript ENSMUST00000057194 Ensembl | MGI Sequence Detail 1984 Not Applicable  
polypeptide ENSMUSP00000062489 Ensembl | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory