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Tapt1 Gene Detail
Summary
  • Symbol
    Tapt1
  • Name
    transmembrane anterior posterior transformation 1
  • Synonyms
    4932414K18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683537
    NCBI Gene: 231225
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:44332496-44383968 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 24.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683537
 protein coding gene Chr5:44332496-44384411 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029529
 protein coding gene Chr5:42813901-42868088 (-)
A/J MGP_AJ_G0029496
 protein coding gene Chr5:41340581-41391996 (-)
AKR/J MGP_AKRJ_G0029445
 protein coding gene Chr5:42799223-42850654 (-)
BALB/cJ MGP_BALBcJ_G0029506
 protein coding gene Chr5:41811643-41863024 (-)
C3H/HeJ MGP_C3HHeJ_G0029229
 protein coding gene Chr5:42785729-42837667 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029960
 protein coding gene Chr5:44877198-44929564 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027199
 protein coding gene Chr5:38557947-38609279 (-)
CAST/EiJ MGP_CASTEiJ_G0028637
 protein coding gene Chr5:41905805-41956569 (-)
CBA/J MGP_CBAJ_G0029198
 protein coding gene Chr5:46058718-46110714 (-)
DBA/2J MGP_DBA2J_G0029343
 protein coding gene Chr5:41426966-41478373 (-)
FVB/NJ MGP_FVBNJ_G0029304
 protein coding gene Chr5:40857374-40909332 (-)
LP/J MGP_LPJ_G0029429
 protein coding gene Chr5:43279473-43331967 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029332
 protein coding gene Chr5:46865823-46918133 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029993
 protein coding gene Chr5:42289765-42341137 (-)
PWK/PhJ MGP_PWKPhJ_G0028361
 protein coding gene Chr5:40565855-40616316 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028195
 protein coding gene Chr5:41732209-41785047 (-)
WSB/EiJ MGP_WSBEiJ_G0028718
 protein coding gene Chr5:42384365-42436767 (-)



Homology
more
  • Human Ortholog
    TAPT1, transmembrane anterior posterior transformation 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAPT1, transmembrane anterior posterior transformation 1
  • Synonyms
    CMVFR, OCLSBG
  • Links
    NCBI Gene ID: 202018
    neXtProt AC: NX_Q6NXT6
    UniProt: Q6NXT6

  • Chr Location
    4p15.32; chr4:16160505-16227410 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU mutation causing a truncation exhibit vertebral trasnformations and defects in rib attachment and the xiphoid process. Mice homozygous for a transgenic gene disruption exhibit cleft palate and possible anemia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    18
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046985 Ensembl Gene Model | MGI Sequence Detail 51473 C57BL/6J ±  kb
    transcript ENSMUST00000055128 Ensembl | MGI Sequence Detail 3513 Not Applicable  
    polypeptide ENSMUSP00000062110 Ensembl | MGI Sequence Detail 564 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 9
      Primer pair 3

      Microarray probesets 4
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 7
      Phenotypes 25
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory