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Cfap221 Gene Detail
Summary
  • Symbol
    Cfap221
  • Name
    cilia and flagella associated protein 221
  • Synonyms
    Gm101, Pcdp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684947
    NCBI Gene: 226356
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:119851071-119924964 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.54 cM, cytoband E2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1857 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684947
 protein coding gene Chr1:119851070-119934624 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016400
 protein coding gene Chr1:122697715-122766644 (-)
A/J MGP_AJ_G0016383
 protein coding gene Chr1:118300794-118371273 (-)
AKR/J MGP_AKRJ_G0016348
 protein coding gene Chr1:121787220-121855876 (-)
BALB/cJ MGP_BALBcJ_G0016343
 protein coding gene Chr1:118561013-118633967 (-)
C3H/HeJ MGP_C3HHeJ_G0016169
 protein coding gene Chr1:121952372-122022868 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016804
 protein coding gene Chr1:127372666-127449936 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014517
 protein coding gene Chr1:111951032-112025557 (-)
CAST/EiJ MGP_CASTEiJ_G0015750
 protein coding gene Chr1:120733975-120812858 (-)
CBA/J MGP_CBAJ_G0016142
 protein coding gene Chr1:131780125-131861280 (-)
DBA/2J MGP_DBA2J_G0016248
 protein coding gene Chr1:117323323-117393812 (-)
FVB/NJ MGP_FVBNJ_G0016247
 protein coding gene Chr1:116073355-116144738 (-)
LP/J MGP_LPJ_G0016319
 protein coding gene Chr1:124041814-124119503 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016272
 protein coding gene Chr1:137533615-137602616 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016840
 protein coding gene Chr1:121498892-121576373 (-)
PWK/PhJ MGP_PWKPhJ_G0015536
 protein coding gene Chr1:116298507-116373041 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015324
 protein coding gene Chr1:120390286-120467556 (-)
WSB/EiJ MGP_WSBEiJ_G0015812
 protein coding gene Chr1:121381175-121454851 (-)



Homology
more
  • Human Ortholog
    CFAP221, cilia and flagella associated protein 221
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP221, cilia and flagella associated protein 221
  • Synonyms
    FAP221, PCDP1
  • Links
    NCBI Gene ID: 200373
    neXtProt AC: NX_Q4G0U5
    UniProt: Q4G0U5

  • Chr Location
    2q14.2; chr2:119544432-119662251 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036962 Ensembl Gene Model | MGI Sequence Detail 73894 C57BL/6J ±  kb
transcript ENSMUST00000174370 Ensembl | MGI Sequence Detail 2871 Not Applicable  
polypeptide ENSMUSP00000134576 Ensembl | MGI Sequence Detail 836 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:294202 McKenzie CW, et al., Genetic interaction between central pair apparatus genes CFAP221, CFAP54, and SPEF2 in mouse models of primary ciliary dyskinesia. Sci Rep. 2020 Jul 23;10(1):12337
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory