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Sbspon Gene Detail
Summary
  • Symbol
    Sbspon
  • Name
    somatomedin B and thrombospondin, type 1 domain containing
  • Synonyms
    Gm106, LOC226866
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684952
    NCBI Gene: 226866
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:15924086-15962946 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 4.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1208 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684952
 protein coding gene Chr1:15924086-15962946 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015851
 protein coding gene Chr1:13328287-13361697 (-)
A/J MGP_AJ_G0015832
 protein coding gene Chr1:13197413-13236103 (-)
AKR/J MGP_AKRJ_G0015791
 protein coding gene Chr1:13203763-13241320 (-)
BALB/cJ MGP_BALBcJ_G0015788
 protein coding gene Chr1:12912216-12948802 (-)
C3H/HeJ MGP_C3HHeJ_G0015622
 protein coding gene Chr1:13204337-13239644 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016242
 protein coding gene Chr1:13906194-13942671 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013963
 protein coding gene Chr1:11832547-11865815 (-)
CAST/EiJ MGP_CASTEiJ_G0015203
 protein coding gene Chr1:13297888-13335036 (-)
CBA/J MGP_CBAJ_G0015595
 protein coding gene Chr1:14242621-14279207 (-)
DBA/2J MGP_DBA2J_G0015694
 protein coding gene Chr1:12791282-12826324 (-)
FVB/NJ MGP_FVBNJ_G0015699
 protein coding gene Chr1:12594108-12633428 (-)
LP/J MGP_LPJ_G0015766
 protein coding gene Chr1:13534169-13569405 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015718
 protein coding gene Chr1:14915046-14946899 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016289
 protein coding gene Chr1:13138034-13179215 (-)
PWK/PhJ MGP_PWKPhJ_G0014987
 protein coding gene Chr1:12576489-12610670 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014768
 protein coding gene Chr1:13328621-13364595 (-)
WSB/EiJ MGP_WSBEiJ_G0015266
 protein coding gene Chr1:13100667-13137971 (-)



Homology
more
  • Human Ortholog
    SBSPON, somatomedin B and thrombospondin type 1 domain containing
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SBSPON, somatomedin B and thrombospondin type 1 domain containing
  • Synonyms
    C8orf84, RPESP
  • Links
    NCBI Gene ID: 157869
    neXtProt AC: NX_Q8IVN8
    UniProt: Q8IVN8

  • Chr Location
    8q21.11; chr8:73064543-73124088 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    32
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 226866 NCBI Gene Model | MGI Sequence Detail 38861 C57BL/6J ±  kb
    transcript NM_001033288 RefSeq | MGI Sequence Detail 2748 C57BL/6  
    polypeptide Q3UPR9 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000014180 somatomedin-B and thrombospondin type-1 domain-containing protein
      (term hierarchy)
    • InterPro Domains
      IPR039942 Somatomedin-B and thrombospondin type-1 domain-containing protein
      IPR001212 Somatomedin B domain
      IPR036024 Somatomedin B-like domain superfamily
      IPR044004 Spondin-like TSP1 domain
      IPR000884 Thrombospondin type-1 (TSP1) repeat
      IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
    • GlyGen
      Q3UPR9 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 8
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory